4-Amino-2-Methylphenol(CAS: 2635-95-2)

4-Amino-2-Methylphenol is a white crystalline solid with a molecular weight of approximately 149.17 g/mol. It is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. Chemically, it is reactive and can participate in various organic reactions such as nucleophilic substitution and electrophilic aromatic substitution.

4-Amino-2-Methylphenol is typically synthesized through the reduction of 2-methylphenylisocyanate with sodium borohydride. The reaction is carried out under mild conditions with good yield and selectivity. Other methods may involve the direct amination of 2-methylbenzaldehyde using ammonia or an amine derivative.

4-Amino-2-Methylphenol is used in various industries, particularly in pharmaceuticals where it serves as a precursor for the synthesis of active pharmaceutical ingredients. It is also used in the production of dyes, pigments, and as a chemical intermediate in the synthesis of other organic compounds.

When handling 4-Amino-2-Methylphenol, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. It should be stored in a cool, dry, well-ventilated area away from strong acids and bases. In case of spill, avoid direct contact and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.