4-Vinylphenol | CAS No. 2628-17-3

4-Vinylphenol

Basic Information

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CAS Number

2628-17-3

Molecular Formula

C8H8O

Molecular Weight

120.15 g/mol

Chemical Classification

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Liquid

Melting Point

73 ºC

Boiling Point

206.2°C at 760 mmHg

Water Solubility

Slightly miscible with water.

Flash Point

>230 °F

Refractive Index

1.4440

SMILES

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Oc1ccc(C=C)cc1

InChI

InChI=1S/C8H8O/c1-2-7-3-5-8(9)6-4-7/h2-6,9H,1H2

InChIKey

FUGYGGDSWSUORM-UHFFFAOYSA-N

LogP

2.0351999999999997

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

90.7

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

4-Vinylphenol
4-Hydroxystyrene
p-Vinylphenol
4-ethenylphenol
4-Vinylphenol0.1
1-hydroxy-4-vinylbenzene
para-hydroxystyrene
Phenol,4-ethenyl
Phenol,P-vinyl
p-Hydroxystyrene
4-Vinylphenol, ca Soln. in Propylene Glycol
Phenol, 4-ethenyl-
Phenol, P-vinyl-
4-Ethenyl-phenol
FEMA No. 3739
Poly(4-hydroxystyrene)
OA7V1SM8YL
FUGYGGDSWSUORM-UHFFFAOYSA-N
paravinyl phenol
Para-vinylphenol
p-vinyl phenol
4-VP
Phenol, polymers
4-Hydroxystyrene solution

MDL Number

MFCD00017593

FAQ

What are the physical and chemical properties of 4-Vinylphenol (CAS: 2628-17-3)?

4-Vinylphenol (CAS: 2628-17-3) is a white crystalline solid with a molecular weight of 128.16 g/mol. It has a melting point of 53-54°C and a boiling point of 225-227°C. This compound is slightly soluble in water but soluble in organic solvents such as ethanol and acetone. It is reactive towards bases and reducing agents, making it an important intermediate in organic synthesis.

How is 4-Vinylphenol (CAS: 2628-17-3) typically synthesized?

4-Vinylphenol (CAS: 2628-17-3) is commonly synthesized via the reduction of 4-chlorophenyl vinyl ether using sodium borohydride as the reducing agent. The reaction is carried out in dichloromethane under mild conditions, providing good yield and selectivity. Other methods include the reaction of 4-hydroxybenzaldehyde with acetylene or the alkylation of phenol with vinyl chloride.

What industries use 4-Vinylphenol (CAS: 2628-17-3)?

4-Vinylphenol (CAS: 2628-17-3) is widely used in the pharmaceutical, polymer, and sensor industries. In pharmaceuticals, it is used as an intermediate in the synthesis of certain drugs. In the polymer industry, it serves as a monomer for the production of polymers with specific properties. Additionally, it is utilized in the synthesis of organic sensors due to its sensitivity to certain chemical species.

What precautions should be taken when handling 4-Vinylphenol (CAS: 2628-17-3)?

When handling 4-Vinylphenol (CAS: 2628-17-3), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with absorbent materials and neutralized with water before disposal. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.