4-Vinylphenol(CAS: 2628-17-3)

4-Vinylphenol (CAS: 2628-17-3) is a white crystalline solid with a molecular weight of 128.16 g/mol. It has a melting point of 53-54°C and a boiling point of 225-227°C. This compound is slightly soluble in water but soluble in organic solvents such as ethanol and acetone. It is reactive towards bases and reducing agents, making it an important intermediate in organic synthesis.

4-Vinylphenol (CAS: 2628-17-3) is commonly synthesized via the reduction of 4-chlorophenyl vinyl ether using sodium borohydride as the reducing agent. The reaction is carried out in dichloromethane under mild conditions, providing good yield and selectivity. Other methods include the reaction of 4-hydroxybenzaldehyde with acetylene or the alkylation of phenol with vinyl chloride.

4-Vinylphenol (CAS: 2628-17-3) is widely used in the pharmaceutical, polymer, and sensor industries. In pharmaceuticals, it is used as an intermediate in the synthesis of certain drugs. In the polymer industry, it serves as a monomer for the production of polymers with specific properties. Additionally, it is utilized in the synthesis of organic sensors due to its sensitivity to certain chemical species.

When handling 4-Vinylphenol (CAS: 2628-17-3), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled with absorbent materials and neutralized with water before disposal. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.