(2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid

Basic Information

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CAS Number

26250-84-0

Molecular Formula

C11H19NO4

Molecular Weight

229.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

122.0 to 126.0 deg-C

Boiling Point

353.2°C at 760 mmHg

Density

1.164

Water Solubility

Insoluble in water.

Flash Point

167.4℃

Refractive Index

1.496

Specific Rotation

-63.2 º (c=1 in acetic acid)

SMILES

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CC(C)(C)OC(=O)N1CCCCC1C(=O)O

InChI

InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-7-5-4-6-8(12)9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m0/s1

InChIKey

JQAOHGMPAAWWQO-QMMMGPOBSA-N

LogP

1.8606

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

282

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(S)-1-N-Boc-Pipecolinic acid
(S)-(-)-1-(tert-butoxycarbonyl)-2-piperidine carboxylic acid
(2s)-piperidine-2-carboxylic acid, n-boc protected
(L)-N-Boc-Pipecolic acid
(S)-1-Boc-2-piperidinecarboxylic Acid
JQAOHGMPAAWWQO-QMMMGPOBSA-N
(2S)-N-(tert-Butyloxycarbonyl)pipecolinic acid
MFCD00151904
(s)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid
(2S)-1-(tert butoxycarbonyl)-2-piperidinecarboxylic acid
1 -(t-Butyloxycarbonyl)-piperidine-2(S)-carboxylic acid
(2s)-1-(tert-butoxycarbonyl)piperidine-2-carboxylic acid
N-Boc-L-pipecolinic acid
(S)-(-)-1-Boc-2-piperidine carboxylic acid
(2S)-Piperidine-1,2-dicarboxylic acid 1-tert-butyl ester
(2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid
B3700
N-(t-Butoxycarbonyl)piperidine-2(S)-carboxylic acid
HY-W007743
(2S)-1-[(tert-butoxy)carbonyl]piperidine-2-carboxylic acid
1-(tert-Butoxycarbonyl)-L-pipecolic Acid
26250-84-0
SCHEMBL65490
Boc-Pip-OH, 98%
BOC-HPro-OH
EN300-71975
Boc-L-Pipecolic acid
Z1033300648
AKOS007930645
1-Boc-L-pipecolic Acid
boc-l-piperidine-2-carboxylic acid

MDL Number

MFCD00151904

Customs Code

2933399090

FAQ

What is (2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid (CAS: 26250-84-0)?

This compound, with the CAS number 26250-84-0, is a derivative of piperidinecarboxylic acid. It features a protected carboxylic acid group linked to a piperidine ring, making it a valuable intermediate in organic synthesis. The chemical formula is C11H21NO4, and it is typically a white solid with a characteristic odor. It is known for its stability under normal conditions and is used in various chemical applications.

What are the main uses of (2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid (CAS: 26250-84-0)?

This compound is primarily used in pharmaceutical research as a building block for the synthesis of various drugs. It also finds applications in chemical manufacturing and as a reagent in organic chemistry experiments. Its unique structure makes it suitable for targeted modifications in drug development, contributing to the creation of compounds with specific biological activities.

Is (2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid (CAS: 26250-84-0) safe?

The safety of this compound depends on exposure conditions. It is generally considered safe when handled properly in a controlled environment. However, it is advisable to use appropriate personal protective equipment (PPE) such as gloves and goggles. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures to ensure compliance with chemical safety standards.

How should (2S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperidinecarboxylic acid (CAS: 26250-84-0) be stored?

This compound should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is best kept in a sealed container to prevent moisture absorption and contamination. Avoid exposure to air and light to maintain stability. Proper storage conditions are essential to ensure its chemical integrity and prolong shelf life.