4-Bromotetrahydro-2H-pyran

Basic Information

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CAS Number

25637-16-5

Molecular Formula

C5H9BrO

Molecular Weight

165.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

61°C/15mmHg

Refractive Index

n20/D 1.497

SMILES

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C1COCCC1Br

InChI

InChI=1S/C5H9BrO/c6-5-1-3-7-4-2-5/h5H,1-4H2

InChIKey

IVBVKTPDEWDNRW-UHFFFAOYSA-N

LogP

1.5603

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AM90079
4-BROMO-TETRAHYDROPYRAN
25637-16-5
EN300-154517
4-Bromotetrahydropyran
4-bromo-tetrahydro-2H-pyran
IVBVKTPDEWDNRW-UHFFFAOYSA-N
CS-W003396
4-bromooxane
B5600
4-bromo-tetrahydro-pyran
monobromo tetrahydropyran
W-206965
4-Bromooxacyclohexane, 4-Bromotetrahydro-2H-pyran
SY002700
5-Hydroxy-1H-indole-2-carboxylic?acid
SCHEMBL622798
GS-4332
HY-W003396
A817934
4-Bromotetrahydro-2H-pyran
FT-0648507
MFCD07371501
4-BROMOOXACYCLOHEXANE
2H-Pyran, 4-bromotetrahydro-
4-bromanyloxane
DTXSID00537841
AKOS005256357
PB24975
4-Bromotetrahyropyran
4-Bromooxacyclohexane

MDL Number

MFCD07371501

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5)?

4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5) is a colorless to white crystalline solid with a molecular weight of approximately 199.03 g/mol. It has a melting point of 48-49°C and is slightly soluble in water. It is a reactive compound that undergoes electrophilic substitution reactions, particularly bromination. It is also known for its ability to form cyclic ethers and is used in organic synthesis.

How is 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5) typically synthesized?

4-Bromotetrahydro-2H-pyran can be synthesized by the reaction of tetrahydro-2H-pyran with bromine. This reaction is typically performed in anhydrous conditions using a suitable solvent such as dichloromethane. The yield of the product is generally good, and the method is known for its simplicity and effectiveness in generating the desired brominated derivative.

What industries use 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5)?

4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5) is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds. It also finds applications in the polymer industry as a monomer for producing functional polymers. Additionally, it is utilized in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5)?

When handling 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.