4-Bromotetrahydro-2H-pyran(CAS: 25637-16-5)

4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5) is a colorless to white crystalline solid with a molecular weight of approximately 199.03 g/mol. It has a melting point of 48-49°C and is slightly soluble in water. It is a reactive compound that undergoes electrophilic substitution reactions, particularly bromination. It is also known for its ability to form cyclic ethers and is used in organic synthesis.

4-Bromotetrahydro-2H-pyran can be synthesized by the reaction of tetrahydro-2H-pyran with bromine. This reaction is typically performed in anhydrous conditions using a suitable solvent such as dichloromethane. The yield of the product is generally good, and the method is known for its simplicity and effectiveness in generating the desired brominated derivative.

4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5) is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds. It also finds applications in the polymer industry as a monomer for producing functional polymers. Additionally, it is utilized in the development of sensors and semiconductors due to its unique chemical properties.

When handling 4-Bromotetrahydro-2H-pyran (CAS: 25637-16-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.