N-Hydroxycyclohexanamine hydrochloride (1:1)

Basic Information

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CAS Number

25100-12-3

Molecular Formula

C6H14ClNO

Molecular Weight

151.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

166-171 °C

Boiling Point

205.9°Cat760mmHg

Water Solubility

Soluble in water.

Flash Point

97.9°C

SMILES

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C1CCC(CC1)NO.Cl

InChI

InChI=1S/C6H13NO.ClH/c8-7-6-4-2-1-3-5-6;/h6-8H,1-5H2;1H

InChIKey

SSVAHXZUFFSFER-UHFFFAOYSA-N

LogP

1.7197

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

59.5

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

N-Cyclohexylhydroxylamine hydrochloride, 97%
Cyclohexanamine,N-hydroxy-,hydrochloride(1:1)
EINECS 246-612-3
N-cyclohexylhydroxylarnine hydrochloride
N-HYDROXYCYCLOHEXANAMINE HYDROCHLORIDE
CYCLOHEXYLHYDROXYLAMMONIUM CHLORIDE
Cyclohexylhydroxylamine HCl
N-hydroxycyclohexylamine hydrochloride
N-CYCLOHEXYLHYDROXYLAMINE HCL
MFCD00012565
SCHEMBL1451195
N-(cyclohexyl)hydroxylamine hydrochloride
R98VSP3T5L
DTXSID80179788
J-015809
UNII-R98VSP3T5L
N-cyclohexylhydroxylamine;hydrochloride
Q27288002
N-Cyclohexylhydroxylaminehydrochloride
Cyclohexanamine, N-hydroxy-, hydrochloride
NS00084072
25100-12-3
CYCLOHEXANAMINE, N-HYDROXY-, HYDROCHLORIDE (1:1)
HYDROXYLAMINE, N-CYCLOHEXYL-, HYDROCHLORIDE
SSVAHXZUFFSFER-UHFFFAOYSA-N
Cyclohexylhydroxylamine hydrochloride
FT-0624226
A817639
N-Cyclohexylhydroxylamine hydrochloride
CS-0155321
cyclohexylhydroxyamine hydrochloride

MDL Number

MFCD00012565

FAQ

What are the physical and chemical properties of N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3)?

N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3) is a white crystalline solid with a molecular weight of approximately 162.67 g/mol. It is slightly soluble in water and has limited solubility in organic solvents. This compound is relatively stable but can react with bases to form the corresponding amine. It has a melting point of about 122-124°C and a pKa of around 8.5.

How is N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3) typically synthesized?

N-Hydroxycyclohexanamine hydrochloride can be synthesized by reacting cyclohexanamine with phosgene in the presence of a base. The reaction is typically carried out in an aprotic solvent like toluene. The yield is around 80-85%, and the product is purified by recrystallization from water or an appropriate organic solvent.

What industries use N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3)?

N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3) is primarily used in the pharmaceutical industry as a starting material for the synthesis of various drugs. It is also used in the polymer industry for the preparation of polymers with specific properties. Additionally, it is utilized in the sensor industry for the development of gas-sensitive materials and in the semiconductor industry for the manufacturing of electronic components.

What precautions should be taken when handling N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3)?

When handling N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be handled by absorbing them with a suitable material and disposing of the waste according to local regulations. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.