N-Hydroxycyclohexanamine hydrochloride (1:1)(CAS: 25100-12-3)

N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3) is a white crystalline solid with a molecular weight of approximately 162.67 g/mol. It is slightly soluble in water and has limited solubility in organic solvents. This compound is relatively stable but can react with bases to form the corresponding amine. It has a melting point of about 122-124°C and a pKa of around 8.5.

N-Hydroxycyclohexanamine hydrochloride can be synthesized by reacting cyclohexanamine with phosgene in the presence of a base. The reaction is typically carried out in an aprotic solvent like toluene. The yield is around 80-85%, and the product is purified by recrystallization from water or an appropriate organic solvent.

N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3) is primarily used in the pharmaceutical industry as a starting material for the synthesis of various drugs. It is also used in the polymer industry for the preparation of polymers with specific properties. Additionally, it is utilized in the sensor industry for the development of gas-sensitive materials and in the semiconductor industry for the manufacturing of electronic components.

When handling N-Hydroxycyclohexanamine hydrochloride (CAS: 25100-12-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be handled by absorbing them with a suitable material and disposing of the waste according to local regulations. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.