4-Methyl-1-indanone

Basic Information

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CAS Number

24644-78-8

Molecular Formula

C10H10O

Molecular Weight

146.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

94-96 °C

Boiling Point

205.81°C (rough estimate)

Refractive Index

1.5530 (estimate)

SMILES

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CC1=C2CCC(=O)C2=CC=C1

InChI

InChI=1S/C10H10O/c1-7-3-2-4-9-8(7)5-6-10(9)11/h2-4H,5-6H2,1H3

InChIKey

RUORWXQKVXTQJJ-UHFFFAOYSA-N

LogP

2.12392

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

174

Synonyms & References

English

4-methyl-indan-1-one
24644-78-8
4-methylindanone
DTXSID40403076
AC-23413
SY023823
DS-2304
2,3-Dihydro-4-methyl-1H-inden-1-one
1H-Inden-1-one, 2,3-dihydro-4-methyl-
A817415
MFCD00015759
A807522
AM872
4-Methyl-1-indanone
4-methyl-2,3-dihydro-1H-inden-1-one
Methyl-1-indanone
UNII-9W4Y2I8BMW
CS-W004334
A853370
SCHEMBL163780
4-Methyl-indanone
4-methylindan-1-one
4-Methylindan-1-on
EN300-69474
J-015613
Z334686316
4-Methyl-1-indanone, 97%
TS-01900
9W4Y2I8BMW
4-methyl-2,3-dihydroinden-1-one
AKOS000223831

MDL Number

MFCD00015759

Customs Code

2914399090

FAQ

What are the physical and chemical properties of 4-Methyl-1-indanone (CAS: 24644-78-8)?

4-Methyl-1-indanone (CAS: 24644-78-8) is a colorless liquid with a melting point of 64-65°C and a boiling point of 181-183°C. Its molecular weight is approximately 134.21 g/mol. It has a low solubility in water but is miscible with organic solvents. This compound is moderately reactive, particularly towards nucleophiles and electrophiles, and can undergo various chemical transformations such as esterification and alkylation.

How is 4-Methyl-1-indanone (CAS: 24644-78-8) typically synthesized?

4-Methyl-1-indanone (CAS: 24644-78-8) is commonly synthesized by the reaction of 1-indanone with methyl iodide in the presence of a base like sodium hydroxide. This process yields the compound with high selectivity and good yield. Other methods include the reaction of 1-indanone with other methylating agents or through the oxidation of 4-methyl-1-indanone's precursor, 4-methyl-2-indanol.

What industries use 4-Methyl-1-indanone (CAS: 24644-78-8)?

4-Methyl-1-indanone (CAS: 24644-78-8) is used in various industries. In the pharmaceutical sector, it serves as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry for the production of high-performance materials. Additionally, it has applications in the fragrance industry as a raw material for perfumes, and in the sensor and semiconductor industries for specific chemical sensing applications.

What precautions should be taken when handling 4-Methyl-1-indanone (CAS: 24644-78-8)?

When handling 4-Methyl-1-indanone (CAS: 24644-78-8), it is crucial to wear protective equipment such as gloves, goggles, and a lab coat to avoid skin and eye contact. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be cleaned up using appropriate safety equipment. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. Fume hoods should be used during handling to minimize exposure to the vapors.