4-Methyl-1-indanone(CAS: 24644-78-8)

4-Methyl-1-indanone (CAS: 24644-78-8) is a colorless liquid with a melting point of 64-65°C and a boiling point of 181-183°C. Its molecular weight is approximately 134.21 g/mol. It has a low solubility in water but is miscible with organic solvents. This compound is moderately reactive, particularly towards nucleophiles and electrophiles, and can undergo various chemical transformations such as esterification and alkylation.

4-Methyl-1-indanone (CAS: 24644-78-8) is commonly synthesized by the reaction of 1-indanone with methyl iodide in the presence of a base like sodium hydroxide. This process yields the compound with high selectivity and good yield. Other methods include the reaction of 1-indanone with other methylating agents or through the oxidation of 4-methyl-1-indanone's precursor, 4-methyl-2-indanol.

4-Methyl-1-indanone (CAS: 24644-78-8) is used in various industries. In the pharmaceutical sector, it serves as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry for the production of high-performance materials. Additionally, it has applications in the fragrance industry as a raw material for perfumes, and in the sensor and semiconductor industries for specific chemical sensing applications.

When handling 4-Methyl-1-indanone (CAS: 24644-78-8), it is crucial to wear protective equipment such as gloves, goggles, and a lab coat to avoid skin and eye contact. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be cleaned up using appropriate safety equipment. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. Fume hoods should be used during handling to minimize exposure to the vapors.