4-Chloro-5-nitro-2-pyridinamine

Basic Information

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CAS Number

24484-96-6

Molecular Formula

C5H4ClN3O2

Molecular Weight

173.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

240-242°C

Boiling Point

377 ºC

Flash Point

182 ºC

SMILES

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C1=C(C(=CN=C1N)[N+](=O)[O-])Cl

InChI

InChI=1S/C5H4ClN3O2/c6-3-1-5(7)8-2-4(3)9(10)11/h1-2H,(H2,7,8)

InChIKey

LHFAJLRJEULFIT-UHFFFAOYSA-N

LogP

2.32980

Complexity

160

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

3-Hydroxy Rivaroxaban
24484-96-6
2-Amino-4-chloro-5-nitropyridine
LHFAJLRJEULFIT-UHFFFAOYSA-N
PB12821
CS-W003220
DTXSID20408827
4-CHLORO-5-NITRO-PYRIDIN-2-YLAMINE
2-AMINO-4-CHLORO-5-NITROPYRIDINE[24484-96-6]
SCHEMBL57031
4-chloro-5-nitropyridin-2-amine
AKOS005256522
2-Amino-4-chloro-5-nitropyridine;2-Pyridinamine, 4-chloro-5-nitro-
AC-25169
4-chloro-5-nitro-pyridin-2-amine
W-206896
BCP33658
4-Chloro-5-nitropyridine-2-amine
FT-0646056
2-Pyridinamine, 4-chloro-5-nitro-
MFCD04973545
SY024680
2-Pyridinamine,4-chloro-5-nitro-
A5038
AMY5648
EN300-399748
DS-10963
4-Chloro-5-nitropyridin-2-amine
2-Amino-4-Chloro-5-Nitropyridine
2-Amino-4-chloro-5-nitro-pyridine
6-Amino-4-chloro-3-nitropyridine

MDL Number

MFCD04973545

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Chloro-5-nitro-2-pyridinamine (CAS: 24484-96-6)?

4-Chloro-5-nitro-2-pyridinamine is a crystalline solid with a molecular weight of approximately 210.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. This compound is known for its reactivity due to the presence of the nitro and chlorine groups, which can participate in various chemical reactions such as nucleophilic substitution and electrophilic aromatic substitution.

How is 4-Chloro-5-nitro-2-pyridinamine (CAS: 24484-96-6) typically synthesized?

4-Chloro-5-nitro-2-pyridinamine can be synthesized by the nitration of 4-chloro-2-pyridinamine followed by acetylation and hydrolysis. Alternatively, it can be obtained through the chlorination of 5-nitro-2-pyridinamine. The nitration process requires careful control of temperature and concentration to achieve the desired product with good selectivity and yield.

What industries use 4-Chloro-5-nitro-2-pyridinamine (CAS: 24484-96-6)?

4-Chloro-5-nitro-2-pyridinamine is used in various industries, particularly in the pharmaceutical sector for the synthesis of drug intermediates. It also finds application in the production of organic dyes and in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 4-Chloro-5-nitro-2-pyridinamine (CAS: 24484-96-6)?

When handling 4-Chloro-5-nitro-2-pyridinamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Always consult a safety data sheet (SDS) for detailed handling and emergency procedures.