2-Bromo-3-thiophenecarboxylic acid

Basic Information

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CAS Number

24287-95-4

Molecular Formula

C5H3BrO2S

Molecular Weight

207.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

178-182 °C

Boiling Point

313.2°C at 760 mmHg

Flash Point

143.225℃

SMILES

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C1=CSC(=C1C(=O)O)Br

InChI

InChI=1S/C5H3BrO2S/c6-4-3(5(7)8)1-2-9-4/h1-2H,(H,7,8)

InChIKey

RVSXMPCELBYUSF-UHFFFAOYSA-N

LogP

2.2088

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

128

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

EN300-112383
Z1269180691
3-Thiophenecarboxylic acid, 2-bromo-
2-bromo-3-thiophene carboxylic acid
BCP08081
FT-0647023
SY016339
CS-D0553
RVSXMPCELBYUSF-UHFFFAOYSA-N
MFCD05865213
2-Naphthaleneylboronicacid
DS-12410
AKOS005264313
2-Bromothiophene-3-carboxylic?acid
SCHEMBL852028
AC-33268
2-bromothiophene-3-carboxylicacid
DTXSID50488551
2-bromothiophene-3-carboxylic acid
24287-95-4
W-206884
2-Bromo-thiophene-3-carboxylic acid
2-Bromo-3-thiophenecarboxylic acid, 97%
PB42358
2-Bromo-3-thiophenecarboxylic acid
AMY7270
2-bromo-thiophene 3-carboxylic acid
2-Bromothiophene-3-carboxylic acid
2-Bromo-3-carboxythiophene
3-Thiophenecarboxylicacid, 2-broMo-
2-BROMO-3-THIOPHENE CARBOXYLIC ACID

MDL Number

MFCD05865213

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Bromo-3-thiophenecarboxylic acid (CAS: 24287-95-4)?

2-Bromo-3-thiophenecarboxylic acid is a solid with a crystalline form. It has a molecular weight of approximately 207.02 g/mol. This compound is slightly soluble in water but more soluble in organic solvents. It is moderately reactive and can undergo bromine substitution and carboxylic acid reactions. It is a weak acid due to the presence of the carboxylic acid group.

How is 2-Bromo-3-thiophenecarboxylic acid (CAS: 24287-95-4) typically synthesized?

2-Bromo-3-thiophenecarboxylic acid is typically synthesized by bromination of 3-thiophenecarboxylic acid using N-bromosuccinimide (NBS) in the presence of a suitable solvent like dichloromethane. The reaction is carried out under mild conditions to achieve good yield and selectivity. Other methods include direct bromination with bromine in the presence of a phase-transfer catalyst.

What industries use 2-Bromo-3-thiophenecarboxylic acid (CAS: 24287-95-4)?

2-Bromo-3-thiophenecarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs due to its structural properties. It is also utilized in the polymer industry for the development of advanced materials. Additionally, it finds applications in the production of sensors and as a functional group in semiconductor manufacturing processes.

What precautions should be taken when handling 2-Bromo-3-thiophenecarboxylic acid (CAS: 24287-95-4)?

When handling 2-Bromo-3-thiophenecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or under a fume hood to minimize exposure. Proper storage should be ensured in a cool, dry place away from direct sunlight and heat sources. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.