(2S)-2-amino-3-(4-bromophenyl)propanoic acid

Basic Information

View in Editor

CAS Number

24250-84-8

Molecular Formula

C9H10BrNO2

Molecular Weight

244.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

~265 °C (dec.)

Boiling Point

368.4℃ at 760 mmHg

Density

1.588

Flash Point

176.6 oC

Specific Rotation

-17° (c=1,H2O)

SMILES

View in Editor

C1=CC(=CC=C1CC(C(=O)O)N)Br

InChI

InChI=1S/C9H10BrNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

InChIKey

PEMUHKUIQHFMTH-QMMMGPOBSA-N

LogP

1.4035000000000002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

179

Safety Information

View Safety Information

GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

P-BROMO-L-PHENYLALANINE
Q-101613
L-Phenylalanine, 4-bromo-
J-300375
L-p-Bromophenylalanine
BP-20585
4-Bromophenylalanine
24250-84-8
Q27454571
IS_4-BROMO-PHENYLALANINE
NS00052242
SCHEMBL44832
4-Bromo-L-phenylalanine, >=98.0% (NT)
l-4-br-phe-oh
J-511572
AC-5856
(S)-2-amino-3-(4-bromophenyl)propanoic acid;(S)-3-(P-BROMOPHENYL)-BETA-ALANINE
l-4-bromo phenylalanine
GS-6454
4BF
HY-34597
EN300-217027
PEMUHKUIQHFMTH-QMMMGPOBSA-N
h-phe(4-br)-oh
L-4-Bromophenylalanine
(S)-4-BromophenylalanineHydrochloride
AKOS010398002
(2S)-2-amino-3-(4-bromophenyl)propanoic acid
P-BROMOPHENYLALANINE
(s)-2-amino-3-(4-bromophenyl)propanoic acid
AM20060568

MDL Number

MFCD00063062

FAQ

What are the physical and chemical properties of (2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8)?

(2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8) is a white crystalline solid with a molecular weight of approximately 288.03 g/mol. It has a low solubility in water (0.1 g/L at 20°C) and is more soluble in organic solvents. This compound is reactive, particularly with bases and nucleophiles, and can undergo substitution and condensation reactions.

How is (2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8) typically synthesized?

(2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8) is typically synthesized by bromination of 2-amino-3-phenylpropanoic acid followed by coupling with bromobenzene. Common synthetic methods include the use of N-bromosuccinimide (NBS) as a brominating agent under UV light, and the reaction is carried out in a suitable organic solvent such as dichloromethane. The yield is generally high, around 70-80%, and the reaction is selective and provides good purity.

What industries use (2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8)?

(2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8) is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the polymer industry as a monomer for the production of certain types of polymers. Additionally, it can be used in the development of sensors and semiconductors due to its structural properties.

What precautions should be taken when handling (2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8)?

When handling (2S)-2-amino-3-(4-bromophenyl)propanoic acid (CAS: 24250-84-8), proper personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposed of in accordance with local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.