Econazole nitrate | CAS No. 24169-02-6

Q: What is Econazole nitrate (CAS: 24169-02-6)?

Econazole nitrate is an antifungal medication with the chemical formula C17H17N3O4S. It is a white to pale yellow powder that is soluble in water and commonly used in topical formulations. The compound is known for its broad-spectrum antifungal activity and is often found in over-the-counter creams and lotions for treating fungal infections.

Q: What are the main uses of Econazole nitrate (CAS: 24169-02-6)?

Econazole nitrate is primarily used in the treatment of fungal infections such as athlete's foot, jock itch, and ringworm. It is also incorporated into pharmaceutical products for conditions like tinea versicolor and candidiasis. In industrial applications, it may be used as a fungicide in agricultural or cosmetic products.

Q: Is Econazole nitrate (CAS: 24169-02-6) safe?

Econazole nitrate is generally considered safe when used as directed, with low toxicity in topical applications. However, it should be handled with care to avoid skin irritation or allergic reactions. Proper protective measures, such as gloves, are recommended during handling, and safety standards ensure its use in regulated medical and consumer products.

Q: How should Econazole nitrate (CAS: 24169-02-6) be stored?

Econazole nitrate should be stored in a cool, dry place away from direct light. It is stable under normal storage conditions but should be kept in a sealed container to prevent moisture absorption. Maintaining a temperature range of 15-30°C and humidity levels below 60% ensures optimal shelf life and product integrity.

Econazole nitrate

Basic Information

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CAS Number

24169-02-6

Molecular Formula

C18H15Cl3N2O.HNO3

Molecular Weight

444.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

162 ºC

Boiling Point

°Cat760mmHg

Density

0.8620

Water Solubility

<0.1 g/100 mL at 19 ºC

Solubility

chloroform/methanol: soluble25mg/mL (choloroform:methanol (1:1))

SMILES

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C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]

InChI

InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

InChIKey

DDXORDQKGIZAME-UHFFFAOYSA-N

LogP

5.97690

Complexity

404

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Toxicity

LD50 in mice, rats (mg/kg): 462.7, 667.7 orally (Thienpont)

Synonyms & References

English

1-[2-(4-Chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Nitrate
EINECS 246-053-5
CCG-38966
SPECTRUM1501185
ECONAZOLE NITRATE (EP IMPURITY)
CHEBI:4755
Opera_ID_1393
24169-02-6
Pharmakon1600-01501185
SQ-13050
ECONAZOLE NITRATE [MI]
NCGC00094926-04
1-[2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
Econazole nitrate salt
DTXSID6025226
NSC757882
1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole nitrate;Econazole nitrate
Gyno-pevaryl
NSC 243115
ECONAZOLE NITRATE (USP-RS)
A817124
1H-IMIDAZOLE, 1-(2-((4-CHLOROPHENYL)METHOXY)-2-(2,4-DICHLOROPHENYL)ETHYL)-, (+-)-, MONONITRATE
R 14,827
SW196500-3
1-(2-((4-chloro-phenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole Mononitrate
Econazole nitrate (USAN:USP:BAN:JAN)
HMS1568N10
1H-Imidazole,4-dichlorophenyl]ethyl)-, nitrate
Palavale
A836253
MLS002415728

MDL Number

MFCD00058160

Customs Code

2933290090

FAQ

What is Econazole nitrate (CAS: 24169-02-6)?

Econazole nitrate is an antifungal medication with the chemical formula C17H17N3O4S. It is a white to pale yellow powder that is soluble in water and commonly used in topical formulations. The compound is known for its broad-spectrum antifungal activity and is often found in over-the-counter creams and lotions for treating fungal infections.

What are the main uses of Econazole nitrate (CAS: 24169-02-6)?

Econazole nitrate is primarily used in the treatment of fungal infections such as athlete's foot, jock itch, and ringworm. It is also incorporated into pharmaceutical products for conditions like tinea versicolor and candidiasis. In industrial applications, it may be used as a fungicide in agricultural or cosmetic products.

Is Econazole nitrate (CAS: 24169-02-6) safe?

Econazole nitrate is generally considered safe when used as directed, with low toxicity in topical applications. However, it should be handled with care to avoid skin irritation or allergic reactions. Proper protective measures, such as gloves, are recommended during handling, and safety standards ensure its use in regulated medical and consumer products.

How should Econazole nitrate (CAS: 24169-02-6) be stored?

Econazole nitrate should be stored in a cool, dry place away from direct light. It is stable under normal storage conditions but should be kept in a sealed container to prevent moisture absorption. Maintaining a temperature range of 15-30°C and humidity levels below 60% ensures optimal shelf life and product integrity.