1-(2-Chloroethyl)-2-imidazolidinone

Basic Information

View in Editor

CAS Number

2387-20-4

Molecular Formula

C5H9ClN2O

Molecular Weight

148.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Boiling Point

347.5°C at 760 mmHg

SMILES

View in Editor

C1CN(C(=O)N1)CCCl

InChI

InChI=1S/C5H9ClN2O/c6-1-3-8-4-2-7-5(8)9/h1-4H2,(H,7,9)

InChIKey

YGSFFDHIYYOVHV-UHFFFAOYSA-N

LogP

0.2504

Topological Polar Surface Area

32.34 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

118

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H320 Causes eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AKOS005215881
J-502988
1-(2-Chloroethyl)-2-imidazolidinone #
UNII-BNT494P6EH
EN300-214800
2-Imidazolidinone, 1-(2-chloroethyl)-
FT-0630012
NSC-76791
MFCD09029607
AMY784
AC-8747
SY198208
1-(2-Chloroethyl)-2-imidazolidinone
EINECS 219-212-1
2387-20-4
1-(2-chloroethyl)-imidazolidin-2-one
1-(2-chloroethyl)-2-imidazolidinon
BNT494P6EH
1-(2-chloroethyl)imidazolidine-2-one
CS-0062222
NSC76791
(2-chloroethyl)imidazolidin-2-one
1-(2-Chloroethyl)imidazolidin-2-one
DTXSID60178572
nsc 76791
NS00027495
FF-0057
SCHEMBL360815
1-(2-Chloroethyl) imidazolidin-2-one
2-chloroethylimidazolidone
chloroethylimidazolidinone

MDL Number

MFCD09029607

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-(2-Chloroethyl)-2-imidazolidinone (CAS: 2387-20-4)?

1-(2-Chloroethyl)-2-imidazolidinone is a colorless or white crystalline solid with a molecular weight of approximately 172.61 g/mol. It has a solubility of 1.1 g/L in water and is soluble in organic solvents like ethanol and acetone. This compound is moderately reactive, particularly with nucleophiles and reducing agents. It is highly basic with a pKa of 13.2.

How is 1-(2-Chloroethyl)-2-imidazolidinone (CAS: 2387-20-4) typically synthesized?

1-(2-Chloroethyl)-2-imidazolidinone can be synthesized through the reaction of 2-chloroethylamine with imidazolidinone. The synthesis involves condensation under basic conditions, typically using sodium hydroxide as a catalyst. The yield is generally around 85%, with high selectivity towards the desired product.

What industries use 1-(2-Chloroethyl)-2-imidazolidinone (CAS: 2387-20-4)?

1-(2-Chloroethyl)-2-imidazolidinone is used in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the production of antifungal drugs. It also finds applications in polymers as a stabilizer and in the field of sensors due to its reactivity and stability.

What precautions should be taken when handling 1-(2-Chloroethyl)-2-imidazolidinone (CAS: 2387-20-4)?

Handling 1-(2-Chloroethyl)-2-imidazolidinone requires caution due to its basic nature and potential for skin and eye irritation. Use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood. In case of spill, immediately clean up using appropriate absorbent materials and dispose of waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and safety measures.