2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate | CAS No. 2375424-00-1
2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate
Basic Information
CAS Number
2375424-00-1
Molecular Formula
C11H22N2O3
Molecular Weight
230.31 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- (2S,5S)-tert-Butyl 5-(hydroxymethyl)-2-methylpiperazine-1-carboxylate
- tert-butyl (2S,5S)-5-(hydroxymethyl)-2-methylpiperazine-1-carboxylate
- tert-butyl(2S,5S)-5-(hydroxymethyl)-2-methylpiperazine-1-carboxylate
- Schembl21563173
MDL Number
MFCD32659917
FAQ
What are the physical and chemical properties of 2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate (CAS: 2375424-00-1)?
2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate is a solid compound with a molecular weight of approximately 273.36 g/mol. It has a crystalline form with a melting point of 105-107°C. The compound is slightly soluble in water and has a pKa of 8.1. It is reactive towards bases and can form salts. It is also susceptible to hydrolysis under basic conditions.
How is 2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate (CAS: 2375424-00-1) typically synthesized?
2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate is usually synthesized via a multi-step process involving the protection of the primary amine, followed by reaction with a chloroacetic acid derivative, and subsequent deprotection. This process typically involves the use of protecting groups such as tert-butyldimethylsilyl (TBDMS), and the reaction is performed under mild acidic conditions. The overall yield is around 70-80%, with good regioselectivity and enantioselectivity.
What industries use 2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate (CAS: 2375424-00-1)?
2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate is primarily used in the pharmaceutical industry for the synthesis of various biologically active compounds. It is also employed in the polymer industry for modifying the properties of polymers and in the sensor industry for developing chemical sensors due to its reactivity and functional groups.
What precautions should be taken when handling 2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate (CAS: 2375424-00-1)?
When handling 2-Methyl-2-propanyl (2S,5S)-5-(hydroxymethyl)-2-methyl-1-piperazinecarboxylate, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated fume hood to minimize inhalation of vapors. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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