3-Bromo-1H-pyrrolo[3,2-c]pyridine

Basic Information

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CAS Number

23612-36-4

Molecular Formula

C7H5BrN2

Molecular Weight

197.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

357°Cat760mmHg

Density

1.77

Flash Point

169.7°C

Refractive Index

1.727

SMILES

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C1=CN=CC2=C1NC=C2Br

InChI

InChI=1S/C7H5BrN2/c8-6-4-10-7-1-2-9-3-5(6)7/h1-4,10H

InChIKey

RCDKYXWNDBRDRE-UHFFFAOYSA-N

LogP

2.3253999999999992

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

129

Synonyms & References

English

23612-36-4
Ac-3,5-diamino-4-(4-methoxyphenoxy)-Phe-OEt
RCDKYXWNDBRDRE-UHFFFAOYSA-N
SCHEMBL10587
A816799
FT-0656767
MFCD08690126
DTXSID50576947
PS-4748
AKOS006281436
1H-Pyrrolo[3,2-c]pyridine, 3-bromo-
3-Bromo-5-azaindole
W-206836
EN300-729573
3-bromo-1H-pyrrolo[3,2-c]pyridine
PB16059
SY065440
CS-W006499
AMY9458
3-Bromo-1H-pyrrolo[3,2-c]pyridine
1H-Pyrrolo[3,2-c]pyridine,3-bromo-
3-Brom-5-aza-indol
5-aza-3-bromoindole
RP04086
3-bromanyl-1H-pyrrolo[3,2-c]pyridine
AK115942
AB0040734
Y8381
690B126

MDL Number

MFCD08690126

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS: 23612-36-4)?

3-Bromo-1H-pyrrolo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 225.03 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and chloroform. The compound is known for its high reactivity towards nucleophiles and can undergo substitution reactions easily. It exhibits good thermal stability up to 250°C.

How is 3-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS: 23612-36-4) typically synthesized?

3-Bromo-1H-pyrrolo[3,2-c]pyridine is commonly synthesized by bromination of 1H-pyrrolo[3,2-c]pyridine using N-bromosuccinimide (NBS) in anhydrous conditions. The reaction is conducted in the presence of a radical initiator such as benzoyl peroxide. The yield can be improved by optimizing reaction conditions like temperature and solvent choice.

What industries use 3-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS: 23612-36-4)?

3-Bromo-1H-pyrrolo[3,2-c]pyridine is used in the pharmaceutical industry for synthesizing certain medicinal compounds. It is also utilized in the polymer industry for developing functional materials. Additionally, this compound finds applications in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling 3-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS: 23612-36-4)?

Handling 3-Bromo-1H-pyrrolo[3,2-c]pyridine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure operations are conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal recommendations.