3-Bromo-1H-pyrrolo[3,2-c]pyridine(CAS: 23612-36-4)

3-Bromo-1H-pyrrolo[3,2-c]pyridine is a crystalline solid with a molecular weight of approximately 225.03 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and chloroform. The compound is known for its high reactivity towards nucleophiles and can undergo substitution reactions easily. It exhibits good thermal stability up to 250°C.

3-Bromo-1H-pyrrolo[3,2-c]pyridine is commonly synthesized by bromination of 1H-pyrrolo[3,2-c]pyridine using N-bromosuccinimide (NBS) in anhydrous conditions. The reaction is conducted in the presence of a radical initiator such as benzoyl peroxide. The yield can be improved by optimizing reaction conditions like temperature and solvent choice.

3-Bromo-1H-pyrrolo[3,2-c]pyridine is used in the pharmaceutical industry for synthesizing certain medicinal compounds. It is also utilized in the polymer industry for developing functional materials. Additionally, this compound finds applications in sensor technology and semiconductor manufacturing due to its unique chemical properties.

Handling 3-Bromo-1H-pyrrolo[3,2-c]pyridine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure operations are conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal recommendations.