(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine

Basic Information

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CAS Number

23357-52-0

Molecular Formula

C10H13N

Molecular Weight

147.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Liquid

Boiling Point

250 °C

Water Solubility

Soluble in water.

Refractive Index

n20/D 1.565

SMILES

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C1CC(C2=CC=CC=C2C1)N

InChI

InChI=1S/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7,11H2/t10-/m0/s1

InChIKey

JRZGPXSSNPTNMA-JTQLQIEISA-N

LogP

2.0227000000000004

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

133

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

(+)-1-AMINOTETRALIN
(1S)-1,2,3,4-tetrahydronaphthalen-1-amine
(S)-(+)-1-Amino-1,2,3,4-tetrahydronaphthalene
(1S)-1,2,3,4-TETRAHYDRO-.ALPHA.-NAPHTHYLAMINE
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine, ChiPros(R), produced by BASF, 99%
AC-26799
A816685
(1S)-1,2,3,4-tetrahydro-1-naphthalenylamine
T2878
(S)-1-Amino-1,2,3,4-tetrahydro-naphthalene
1-AMINOTETRALIN, (+)-
(S)-(+)-1-Aminotetraline
NS00077382
(s)-amino tetralin
BDBM50023876
(S)-1,2,3,4-tetrahydronaphthaleneamine
(S)-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)AMINE
CB11LAU5CV
STR08071
(1~{S})-1,2,3,4-tetrahydronaphthalen-1-amine
(1S)-(+)-1-Amino-1,2,3,4-tetrahydronaphthalene
CHEMBL39537
SCHEMBL44600
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine
AKOS006341644
1-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-, (1S)-
(1S)-1,2,3,4-tetrahydro-1-naphthylamine
Q27895862
(S)-1,2,3,4-tetrahydro-naphthaien-1-ylamine
MFCD00671630
(S)-1,2,3,4-Tetrahydronaphthalen-1-amine

MDL Number

MFCD00671630

FAQ

What are the physical and chemical properties of (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine (CAS: 23357-52-0)?

(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine is a white crystalline powder with a molecular weight of approximately 174.25. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable under normal conditions but can react with strong oxidizing agents. It has a boiling point of around 280°C and a melting point of 85-87°C.

How is (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine (CAS: 23357-52-0) typically synthesized?

(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine is usually synthesized via reduction of 1-naphthylacetic acid or by catalytic hydrogenation of 1-naphthylacetamide. The reaction typically requires a catalyst like palladium on carbon and is performed under mild hydrogen pressure. The yield is around 80-85%, with good selectivity to the desired stereochemistry.

What industries use (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine (CAS: 23357-52-0)?

(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a precursor for naphthylamine-based additives. Additionally, it has applications in the sensor and semiconductor industries due to its electronic properties.

What precautions should be taken when handling (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine (CAS: 23357-52-0)?

When handling (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine, it is important to wear protective gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and waste should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling guidelines.