Compound Q&A
How is (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine (CAS: 23357-52-0) typically synthesized?
Answer
(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine is usually synthesized via reduction of 1-naphthylacetic acid or by catalytic hydrogenation of 1-naphthylacetamide. The reaction typically requires a catalyst like palladium on carbon and is performed under mild hydrogen pressure. The yield is around 80-85%, with good selectivity to the desired stereochemistry.
About
CAS No
23357-52-0
English Name
(1S)-1,2,3,4-Tetrahydro-1-naphthalenamine
Molecular Formula
C10H13N
Molecular Weight
147.22 g/mol
SMILES
C1CC(C2=CC=CC=C2C1)N
InChIKey
JRZGPXSSNPTNMA-JTQLQIEISA-N
Last Updated: 2025-09-28 13:06
