(2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate

Basic Information

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CAS Number

23214-66-6

Molecular Formula

C17H20O5S

Molecular Weight

336.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

52-55 °C

Boiling Point

515.6°Cat760mmHg

Density

1.253

Refractive Index

1.573

Specific Rotation

-7 º (c=10 in toluene)

SMILES

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CC1=CC=C(C=C1)S(=O)(=O)OCC(COCC2=CC=CC=C2)O

InChI

InChI=1S/C17H20O5S/c1-14-7-9-17(10-8-14)23(19,20)22-13-16(18)12-21-11-15-5-3-2-4-6-15/h2-10,16,18H,11-13H2,1H3/t16-/m1/s1

InChIKey

HBMUWOSOGHUWSS-MRXNPFEDSA-N

LogP

2.278020000000001

Topological Polar Surface Area

72.83000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

417

Synonyms & References

English

CS-0328277
(2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzene-1-sulfonate
J-015037
1,2-Propanediol, 3-(phenylmethoxy)-, 1-(4-methylbenzenesulfonate), (2R)-
(2R)-1-(benzyloxy)-3-[(4-methylbenzenesulfonyl)oxy]propan-2-ol
(R)-3-(Benzyloxy)-2-hydroxypropyl4-methylbenzenesulfonate
23214-66-6
(R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate
YAA21466
(R)-(-)-1-Benzyloxy-3-(p-tosyloxy)-2-propanol
AS-72941
MFCD00134285
(R)-3-(benzyloxy)-2-hydroxypropyl 4-methylbenzene sulfonate
(R)-(')-1-Benzyloxy-3-(p-tosyloxy)-2-propanol
HBMUWOSOGHUWSS-MRXNPFEDSA-N
(R)-(-)-1-Benzyloxy-3-tosyloxy-2-propanol
(r)-1-O-tosyl-3-O-benzylglycerol
(R)-(-)-1-Benzyloxy-3-(p-tosyloxy)-2-propanol, 95%
[(2R)-2-hydroxy-3-phenylmethoxypropyl] 4-methylbenzenesulfonate
AKOS015888854
SCHEMBL4020804
W12755
DTXSID90545778
(R)-(-)-3-Benzyloxy-1,2-propanediol 1-(p-toluenesulfonate)
(R)-(-)-1-Benzyloxy-3-Tosyloxy-2-Propanol
(R)-(?)-1-Benzyloxy-3-(p-tosyloxy)-2-propanol
R(-)-3-BENZYLOXY-1 2-PROPANEDIOL 1-(TO- LUENE-4-SULFONATE)
(2R)-3-benzyloxy-2-hydroxypropyl 4-methylbenzenesulfonate
(R)-1-O-tosyl-3-O-benzylglycerol
1-Benzyl-sn-glycerol 3-tosylate
1-O-benzyl-3-p-toluenesulfonyl-sn-glycerol

MDL Number

MFCD00134285

Customs Code

2909499000

FAQ

What are the physical and chemical properties of (2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS: 23214-66-6)?

(2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate has a crystalline form and a molecular weight of approximately 336.46 g/mol. It has limited solubility in water but is soluble in organic solvents. This compound is reactive and can participate in various chemical reactions such as esterification and sulfonation. It is stable under normal conditions but should be stored in a cool, dry place away from strong oxidizers and acids.

How is (2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS: 23214-66-6) typically synthesized?

(2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate is typically synthesized via a multistep process involving the protection of a hydroxyl group, followed by sulfonation and deprotection. Common reagents used include benzyloxycarbonyl chloride, methylbenzenesulfonic acid, and appropriate bases. The synthesis is usually carried out with high selectivity and yield, although careful control of reaction conditions is necessary to prevent side reactions.

What industries use (2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS: 23214-66-6)?

(2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate is used in the pharmaceutical industry for the synthesis of drugs that require specific functional groups. It is also utilized in the polymer industry as a monomer or as a modifier to improve properties of polymers. Additionally, it has applications in sensor technology and semiconductor manufacturing due to its chemical reactivity and functional groups.

What precautions should be taken when handling (2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS: 23214-66-6)?

When handling (2R)-3-(Benzyloxy)-2-hydroxypropyl 4-methylbenzenesulfonate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for the latest safety information and guidelines.