(4-Aminophenoxy)acetic acid

Basic Information

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CAS Number

2298-36-4

Molecular Formula

C8H9NO3

Molecular Weight

167.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1=CC(=CC=C1N)OCC(=O)O

InChI

InChI=1S/C8H9NO3/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5,9H2,(H,10,11)

InChIKey

GIFGMEWQGDEWKB-UHFFFAOYSA-N

LogP

0.7322

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

152

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

A816456
(p-Aminophenoxy)acetic acid
NIOSH/AF3520000
AF35200000
SR-01000525559
NSC36983
(4-Aminophenoxy)acetic acid
SCHEMBL655820
NSC 36983
Oprea1_812941
EN300-72963
Acetic acid, (p-aminophenoxy)-
MFCD00224890
HMS1378C20
AKOS000103919
Acetic acid, (4-aminophenoxy)-
Acetic acid,2-(4-aminophenoxy)-
(4-amino-phenoxy)-acetic acid, AldrichCPR
CS-0199636
UNII-RP5AG8F6UY
FT-0679420
RP5AG8F6UY
M & B 2754
ChemDiv2_003232
DTXSID60177525
NS00027315
AS-38882
NSC-36983
2-(4-aminophenoxy)aceticacid
2-(4-aminophenoxy)acetic acid
acetic acid, 2-(4-aminophenoxy)-

MDL Number

MFCD00224890

FAQ

What are the physical and chemical properties of (4-Aminophenoxy)acetic acid (CAS: 2298-36-4)?

(4-Aminophenoxy)acetic acid is a white to off-white crystalline solid with a molecular weight of approximately 174.17 g/mol. It is sparingly soluble in water and has a pKa of about 2.75. This compound is reactive towards nucleophiles and can undergo substitution reactions. It is also known for its potential in forming salts and esters.

How is (4-Aminophenoxy)acetic acid (CAS: 2298-36-4) typically synthesized?

(4-Aminophenoxy)acetic acid can be synthesized by the condensation of phenol and acetic anhydride in the presence of a suitable catalyst, such as p-toluenesulfonic acid. The reaction yield is typically high, and the selectivity for the target product is excellent. The process involves heating the mixture to a specific temperature to promote the reaction and then purifying the product using recrystallization or other chromatographic techniques.

What industries use (4-Aminophenoxy)acetic acid (CAS: 2298-36-4)?

(4-Aminophenoxy)acetic acid is primarily used in the pharmaceutical industry for the synthesis of certain organic compounds and in the production of sensors and semiconductors. It is also utilized in the polymer industry for modifying the properties of polymers and in the development of new materials.

What precautions should be taken when handling (4-Aminophenoxy)acetic acid (CAS: 2298-36-4)?

When handling (4-Aminophenoxy)acetic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.