Diphenyl[(2R)-2-pyrrolidinyl]methanol

Basic Information

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CAS Number

22348-32-9

Molecular Formula

C17H19NO

Molecular Weight

253.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

77.0 to 80.0 deg-C

Boiling Point

411.3°C at 760 mmHg

Flash Point

133.3℃

Refractive Index

58 ° (C=2, MeOH)

Specific Rotation

59 º (589nm, c=3, MeOH 25 ºC)

SMILES

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C1CC(NC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O

InChI

InChI=1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m1/s1

InChIKey

OGCGXUGBDJGFFY-MRXNPFEDSA-N

LogP

2.674500000000001

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

261

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AKOS005259760
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol, 98%
D56JS74WW2
diphenyl-[(2R)-pyrrolidin-2-yl]methanol
(R)-(+)-.ALPHA.,.ALPHA.-DIPHENYL-2-PYRROLIDINEMETHANOL
AM20060555
(+)-.ALPHA.,.ALPHA.-DIPHENYL-2-PYRROLIDINEMETHANOL
(R)-(+)-alpha,alpha-2-Pyrrolidinemethanol
(R)-Alpha-(2-pyrrolidinyl)benzhydryl alcohol
SCHEMBL100360
.ALPHA.,.ALPHA.-DIPHENYL-D-PROLINOL
D2365
FD1265
2-PYRROLIDINEMETHANOL, .ALPHA.,.ALPHA.-DIPHENYL-, (2R)-
22348-32-9
(R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine
(R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol
(R)-alpha,alpha-diphenyl-2-pyrrolidinemethanol
(2R)-.ALPHA.,.ALPHA.-DIPHENYL-2-PYRROLIDINEMETHANOL
CHEBI:190942
R-(+)-Diphenylprolinol
(S)-(a^')-I+/-,I+/--Diphenyl-2-pyrrolidinemethanol
Q-102726
(R)-.ALPHA.,.ALPHA.-DIPHENYLPROLINOL
AS-12467
Diphenyl(2-pyrrolidinyl)methanol #
alpha,alpha-Diphenyl-D-prolinol
BP-12954
CS-W007880
MFCD00077754
(r)-2-(hydroxydiphenylmethyl)pyrrolidine

MDL Number

MFCD00077754

FAQ

What is Diphenyl[(2R)-2-pyrrolidinyl]methanol (CAS: 22348-32-9)?

Diphenyl[(2R)-2-pyrrolidinyl]methanol is a chemical compound with the CAS number 22348-32-9. It is an organic compound that contains a pyrrolidine ring substituted with a methanol group and two phenyl groups. This compound is known for its structural complexity and is often used in advanced chemical research and pharmaceutical development. It is a white to pale yellow solid at room temperature and has a molecular formula of C18H21NO.

What are the main uses of Diphenyl[(2R)-2-pyrrolidinyl]methanol (CAS: 22348-32-9)?

Diphenyl[(2R)-2-pyrrolidinyl]methanol is primarily used in pharmaceutical research for the development of drugs targeting central nervous system disorders. It serves as an intermediate in the synthesis of various biologically active compounds. Additionally, it finds applications in organic synthesis and as a reagent in chemical research due to its unique structure and functional groups. Its use in industry and food is limited due to potential toxicity and regulatory restrictions.

Is Diphenyl[(2R)-2-pyrrolidinyl]methanol (CAS: 22348-32-9) safe?

Diphenyl[(2R)-2-pyrrolidinyl]methanol is considered toxic and should be handled with care. It may cause skin and eye irritation, and prolonged exposure can lead to more severe health effects. Safety data sheets recommend using appropriate protective equipment, such as gloves and goggles, and working in well-ventilated areas. It is important to follow established safety protocols and regulatory guidelines to ensure safe handling and minimize risks.

How should Diphenyl[(2R)-2-pyrrolidinyl]methanol (CAS: 22348-32-9) be stored?

Diphenyl[(2R)-2-pyrrolidinyl]methanol should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container away from moisture and heat sources. Storage at temperatures below 25°C and in a controlled environment with low humidity is optimal. Avoid exposure to light and keep it in a well-ventilated area to prevent any degradation or safety hazards.