(Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride

Basic Information

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CAS Number

220805-22-1

Molecular Formula

C8H20Cl2N4O2

Molecular Weight

275.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Colorless cryst.

Melting Point

202-204OC

SMILES

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CN(C)C(=NCCCC(C(=O)O)N)N.Cl.Cl

InChI

InChI=1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1

InChIKey

SYLNVYJOPZWPJI-ILKKLZGPSA-N

LogP

-0.10159999999999986

Topological Polar Surface Area

104.94 Å²

Hydrogen Bond Donor/Acceptor

5 / 6

Complexity

215

Safety Information

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Stability

Store at 0-5°C; Moisture Sensitive; Hygroscopic

Synonyms & References

English

PD020673
(2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid dihydrochloride
NS00074244
(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoicaciddihydrochloride
C8H18N4O2.2HCl
220805-22-1
DTXSID40585129
(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid dihydrochloride
NG,NG-Dimethylarginine dihydrochloride
AKOS030241797
(2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid;dihydrochloride
J-014476
HY-113216B
L-Ornithine, N5-[(dimethylamino)iminomethyl]-, hydrochloride (1:2)
MFCD00270857
CS-0142778
Asymmetric dimethylarginine (dihydrochloride)
HB0449
AKOS040744874
asym-Dimethylarginine
Ng,ng-dimethyl-l-arginine,dihydrochloride
NG,NG-DIMETHYL-L-ARGININE DIHYDROCHLORIDE
65005-57-4
L-Ornithine,N5-[(dimethylamino)iminomethyl]-, hydrochloride (1:2)
NG,NG-Dimethylarginine Dihydrochloride
NG,NG-dimethyl-L-Arginine (hydrochloride)
(2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid,dihydrochloride
asym-Dimethylarginine ADMA
ADMA

MDL Number

MFCD00270857

FAQ

What are the physical and chemical properties of (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1)?

The (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1) is a crystalline compound with a molecular weight of approximately 300.96 g/mol. It exhibits high solubility in water and moderate solubility in organic solvents. This compound is moderately reactive, particularly under basic conditions. It is stable under normal temperature and pressure conditions but should be stored away from strong acids to prevent hydrolysis.

How is (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1) typically synthesized?

The (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1) is synthesized through a multi-step process involving the reaction of L-ornithine with dimethylamine in the presence of a suitable catalyst. The yield typically ranges from 70% to 80%, with high selectivity for the desired dihydrochloride product. Commonly used solvents include ethanol and water, and the reaction is conducted under mild conditions to ensure product purity.

What industries use (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1)?

The (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1) is primarily used in the pharmaceutical and biotechnology industries for its potent pharmacological properties. It also finds applications in the development of sensors and in the synthesis of certain polymer structures. Additionally, it is employed in the production of some semiconductors for its specific reactivity and stability.

What precautions should be taken when handling (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1)?

When handling (Z)-N~5~-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride (CAS: 220805-22-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Operations should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be carefully managed using neutralizing agents and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.