4-Bromo-3-hydroxy-2-naphthoic acid

Basic Information

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CAS Number

2208-15-3

Molecular Formula

C11H7BrO3

Molecular Weight

267.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

231°C

SMILES

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C1=CC=C2C(=C1)C=C(C(=C2Br)O)C(=O)O

InChI

InChI=1S/C11H7BrO3/c12-9-7-4-2-1-3-6(7)5-8(10(9)13)11(14)15/h1-5,13H,(H,14,15)

InChIKey

HBUFBIFPUAHIDX-UHFFFAOYSA-N

LogP

3.006100000000001

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

256

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AKOS009278961
2-Naphthalenecarboxylicacid,4-bromo-3-hydroxy-
2208-15-3
MFCD00094166
NSC53065
DTXSID80176575
NS00027052
NSC-53065
T70581
AC-27915
4-bromo-3-hydroxy-naphthalene-2-carboxylic acid
CS-0449707
4-bromo-3-hydroxy-2-naphthoicacid
1-bromo-2-hydroxy-3-naphthoic acid
NSC 53065
4-bromo-3-hydroxynaphthalene-2-carboxylic acid
4-Bromo-3-hydroxy-2-naphthoic acid
HBUFBIFPUAHIDX-UHFFFAOYSA-N
EINECS 218-632-2
SCHEMBL569691
3-hydroxy-4-bromo-2-naphthalene carboxylic acid
SY053571
CAA20815
AS-61810
B3229
4-Bromo-3-hydroxy-2-naphthoic Acid
2-Naphthalenecarboxylicacid, 4-bromo-3-hydroxy-
1-Brom-2-hydroxy-3-naphthoesaeure
4-Brom-3-hydroxy-2-naphthalin-carbonsaeure
4-Bromo-3-hydroxy-2-naphthalenecarboxylic acid
STL509280

MDL Number

MFCD00094166

Customs Code

2918290000

FAQ

What are the physical and chemical properties of 4-Bromo-3-hydroxy-2-naphthoic acid (CAS: 2208-15-3)?

4-Bromo-3-hydroxy-2-naphthoic acid is a crystalline solid with a molecular weight of approximately 265.03 g/mol. It has a solubility of about 0.5 g/100 mL in water at 25°C. The compound is relatively stable but can react with bases to form sodium salts. It is insoluble in organic solvents like ethanol and acetone but soluble in dimethylformamide (DMF).

How is 4-Bromo-3-hydroxy-2-naphthoic acid (CAS: 2208-15-3) typically synthesized?

4-Bromo-3-hydroxy-2-naphthoic acid is typically synthesized through bromination of 3-hydroxy-2-naphthoic acid followed by purification. Common methods include the use of N-bromosuccinimide (NBS) in an inert solvent like dichloromethane at room temperature. The reaction is selective and yields a high percentage of the desired brominated product.

What industries use 4-Bromo-3-hydroxy-2-naphthoic acid (CAS: 2208-15-3)?

4-Bromo-3-hydroxy-2-naphthoic acid is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the production of functional materials, such as polymers and sensors, due to its unique chemical properties. Additionally, it has applications in the semiconductor industry for the preparation of photoresists and other electronic materials.

What precautions should be taken when handling 4-Bromo-3-hydroxy-2-naphthoic acid (CAS: 2208-15-3)?

When handling 4-Bromo-3-hydroxy-2-naphthoic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize inhalation hazards. If a spill occurs, it should be contained and disposed of according to local hazardous waste regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.