2,3,5,6-Tetrachloro-4-pyridinamine

Basic Information

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CAS Number

2176-63-8

Molecular Formula

C5H2Cl4N2

Molecular Weight

231.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

212 °C

SMILES

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C1(=C(C(=NC(=C1Cl)Cl)Cl)Cl)N

InChI

InChI=1S/C5H2Cl4N2/c6-1-3(10)2(7)5(9)11-4(1)8/h(H2,10,11)

InChIKey

CPLQYBDXWJHBST-UHFFFAOYSA-N

LogP

3.2774

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

130

Synonyms & References

English

F0345-3365
tetrachloropyridin-4-amine
2,3,5,6-tetrachloro-4-pyridinylamine
2176-63-8
A23622
DTXSID60176159
C5H2Cl4N2
4-Aminotetrachloropyridine
MFCD00183239
4-amino-2,3,5,6-tetrachloropyridine
2,3,5,6-tetrachloropyridin-4-amine
SCHEMBL4375537
VS-00659
AKOS001033343
SR-01000396487-1
4-Pyridinamine, 2,3,5,6-tetrachloro-
CPLQYBDXWJHBST-UHFFFAOYSA-N
SR-01000396487
EU-0001105
EN300-76039
CS-0005513
FT-0688380
Z56761458
AE-641/01147045
D86009
2,3,5,6-tetrachloro-4-pyridinamine
2,3,5,6-Tetrachloropyridin-4-amine
2,3,5,6-Tetrachloro-4-aminopyridine
4-Pyridinamine,2,3,5,6-tetrachloro-
2,3,5,6-Tetrachlor-4-amino-pyridin
2,3,5,6-tetrachloro-pyridin-4-ylamine

MDL Number

MFCD00183239

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8)?

2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8) is a white to off-white crystalline solid with a molecular weight of approximately 251.04 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and chloroform. It is relatively stable but can react with reducing agents. Common applications include its use as a reagent and intermediate in organic synthesis.

How is 2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8) typically synthesized?

2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8) is typically synthesized via the reduction of 2,3,5,6-tetrachloro-4-pyridine with hydrazine hydrate or sodium hydrazide. This reaction involves the addition of hydrazine to the chloride groups to form the amine. Common solvents for this reaction include methanol or ethanol, and the process is carried out under mild conditions to achieve good yield and selectivity.

What industries use 2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8)?

2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8) is used in various industries, including pharmaceuticals, where it serves as a key intermediate in the synthesis of certain drugs. It is also utilized in the production of sensors and some semiconductors due to its chemical reactivity and stability. Additionally, it finds application in polymers and other organic compounds.

What precautions should be taken when handling 2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8)?

Proper handling of 2,3,5,6-Tetrachloro-4-pyridinamine (CAS: 2176-63-8) requires the use of personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be handled in a well-ventilated area or a fume hood due to its potential for inhalation hazards. In case of spills, appropriate spill cleanup procedures should be followed, and the substance should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.