2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine

Basic Information

View in Editor

CAS Number

2164-34-3

Molecular Formula

C9H9BrO2

Molecular Weight

229.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

250-251 °C

Flash Point

>230 °F

Refractive Index

n20/D 1.5720(lit.)

SMILES

View in Editor

C1C(OC2=CC=CC=C2O1)CBr

InChI

InChI=1S/C9H9BrO2/c10-5-7-6-11-8-3-1-2-4-9(8)12-7/h1-4,7H,5-6H2

InChIKey

QYLFKNVZIFTCIY-UHFFFAOYSA-N

LogP

2.2213000000000003

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

152

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

EN300-225890
2-bromomethyl-(2,3 dihydrobenzo[1,4]dioxine)
FT-0653584
2-bromomethyl-(2,3dihydrobenzo[1,4]dioxine)
B2349
2-bromomethylbenzo-1,4-dioxan
QYLFKNVZIFTCIY-UHFFFAOYSA-N
2-(Bromomethyl)-1,4-benzodioxane
FT-0611578
2-(Bromomethyl)-2,3-dihydrobenzo[b][1,4]dioxine
3-(bromomethyl)-2,3-dihydro-1,4-benzodioxine
AS-40113
2-(bromomethyl)-2,3-dihydro-1,4-benzodioxine
QYLFKNVZIFTCIY-UHFFFAOYSA-
2-Bromomethyl-2,3-dihydro-benzo[1,4]dioxine
InChI=1/C9H9BrO2/c10-5-7-6-11-8-3-1-2-4-9(8)12-7/h1-4,7H,5-6H2
SB48494
UNII-T2VR2E695H
2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxin
?2-BROMOMETHYL-1,4-BENZODIOXANE
F1967-1719
T2VR2E695H
6-Methyl-2,3,4,5-tetrahydropyridine N-oxide
NSC-106871
SCHEMBL243878
AKOS016843547
AM100519
NSC106871
AKOS000279184
2-Bromomethyl-2,3-dihydrobenzo[1,4]dioxine
2-bromomethyl-(2,3 dihydrobenzo[1,4]dioxin)

MDL Number

MFCD00044831

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS: 2164-34-3)?

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine is a crystalline solid with a molecular weight of approximately 234.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as dichloromethane and acetone. The compound exhibits moderate reactivity, particularly with nucleophiles, and is used in organic synthesis due to its ability to undergo nucleophilic substitution reactions.

How is 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS: 2164-34-3) typically synthesized?

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine can be synthesized via the electrophilic substitution of 2-bromomethyl-2,3-dihydro-1,4-benzodioxine with appropriate nucleophiles in a suitable organic solvent. Commonly, this involves using bromomethylbenzene and 1,4-benzodioxane in the presence of a base such as sodium hydride or potassium hydroxide.

What industries use 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS: 2164-34-3)?

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine is primarily used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for the modification of polymers. It is also utilized in the production of sensors and semiconductors due to its specific reactivity and chemical properties.

What precautions should be taken when handling 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine (CAS: 2164-34-3)?

Handling 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine requires appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be immediately cleaned up with appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.