2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine(CAS: 2164-34-3)

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine is a crystalline solid with a molecular weight of approximately 234.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as dichloromethane and acetone. The compound exhibits moderate reactivity, particularly with nucleophiles, and is used in organic synthesis due to its ability to undergo nucleophilic substitution reactions.

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine can be synthesized via the electrophilic substitution of 2-bromomethyl-2,3-dihydro-1,4-benzodioxine with appropriate nucleophiles in a suitable organic solvent. Commonly, this involves using bromomethylbenzene and 1,4-benzodioxane in the presence of a base such as sodium hydride or potassium hydroxide.

2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine is primarily used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for the modification of polymers. It is also utilized in the production of sensors and semiconductors due to its specific reactivity and chemical properties.

Handling 2-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine requires appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be immediately cleaned up with appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.