1-(2-Bromophenyl)ethanone

Basic Information

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CAS Number

2142-69-0

Molecular Formula

C8H7BrO

Molecular Weight

199.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

°C

Boiling Point

136°C/28mmHg

Refractive Index

n20/D 1.568(lit.)

SMILES

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CC(=O)C1=CC=CC=C1Br

InChI

InChI=1S/C8H7BrO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,1H3

InChIKey

PIMNFNXBTGPCIL-UHFFFAOYSA-N

LogP

2.651700000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

133

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

o-Bromoacetophenone
Ethanone, 1-(2-bromophenyl)-
Acetophenone, 2'-bromo-
MFCD00000067
SCHEMBL166193
PS-8232
Q63398632
EN300-18196
2'bromoacetophenone
DS-1186
2'-Bromoacetophenone, 99%
1-(2-bromophenyl)ethan-1-one
FT-0611518
J-508502
1-(2-Bromophenyl)ethanone #
2-Acetylbromobenzene
1-(2-Bromophenyl)ethanone
NSC155380
NSC-155380
2 inverted exclamation mark -Bromoacetophenone
1-(2-bromo-phenyl)ethanone
2'-Bromoacetophenone
1-(2-bromo-phenyl)-ethanone
Z219997444
2'-bromoacetophenon
A815337
2`-Bromoacetophenone
ortho-bromoacetophenone
DTXSID90175690
AKOS000119544
CS-W007689

MDL Number

MFCD00000067

Customs Code

29147090

FAQ

What are the physical and chemical properties of 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0)?

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is a white crystalline solid with a molecular weight of approximately 213.01 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is a ketone, which makes it prone to undergo aldol condensation and other reactions involving carbonyl groups.

How is 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) typically synthesized?

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is typically synthesized by the reaction of phenylacetaldehyde with N-bromosuccinimide (NBS) in the presence of a peroxide initiator. The reaction is carried out under mild conditions, yielding the product in good yield with high selectivity. This method is preferred due to its simplicity and the high purity of the product.

What industries use 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0)?

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the preparation of specialized polymers and in the field of sensors for its reactivity and functional properties. Additionally, it has potential applications in semiconductor technology for its electron-donating ability.

What precautions should be taken when handling 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0)?

When handling 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to the vapor. Spills should be handled with caution using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed information on handling and emergency procedures.