1-(2-Bromophenyl)ethanone(CAS: 2142-69-0)

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is a white crystalline solid with a molecular weight of approximately 213.01 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is a ketone, which makes it prone to undergo aldol condensation and other reactions involving carbonyl groups.

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is typically synthesized by the reaction of phenylacetaldehyde with N-bromosuccinimide (NBS) in the presence of a peroxide initiator. The reaction is carried out under mild conditions, yielding the product in good yield with high selectivity. This method is preferred due to its simplicity and the high purity of the product.

1-(2-Bromophenyl)ethanone (CAS: 2142-69-0) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the preparation of specialized polymers and in the field of sensors for its reactivity and functional properties. Additionally, it has potential applications in semiconductor technology for its electron-donating ability.

When handling 1-(2-Bromophenyl)ethanone (CAS: 2142-69-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to the vapor. Spills should be handled with caution using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed information on handling and emergency procedures.