(S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride

Basic Information

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CAS Number

213018-92-9

Molecular Formula

C9H11Cl2NO2

Molecular Weight

236.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

98-100°C

SMILES

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COC(=O)C(C1=CC=CC=C1Cl)N.Cl

InChI

InChI=1S/C9H10ClNO2.ClH/c1-13-9(12)8(11)6-4-2-3-5-7(6)10;/h2-5,8H,11H2,1H3;1H/t8-;/m0./s1

InChIKey

SUUNIMMHDPICBD-QRPNPIFTSA-N

LogP

1.9345999999999997

Topological Polar Surface Area

52.32 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

187

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-(+)-2-chlorophenylglycine methyl ester hydrochloride, AldrichCPR
L-(+)-2-Chlorophenylglycine methyl ester HCl
SCHEMBL1160122
Methyl (alphaS)-alpha-amino-2-chlorobenzeneacetate hydrochloride
SUUNIMMHDPICBD-QRPNPIFTSA-N
A925196
(S)-Methyl 2-amino-2-(2-chlorophenyl)acetate hydrochloride
Methyl (+)-(S)-alpha-amino-alpha-(2-chlorophenyl)acetate hydrochloride
Methyl alpha-amino-alpha-(2-chlorophenyl)acetate hydrochloride, (+)-(S)-
Methyl (2S)-amino(2-chlorophenyl)acetate--hydrogen chloride (1/1)
(S)-Methyl2-amino-2-(2-chlorophenyl)acetatehydrochloride
AKOS016844243
(S)-(+)-2-(2-chlorophenyl)glycine methyl ester hydrochloride
L-(+)-2-Chlorophenylglycine methyl ester hydrochloride (H-L-Phg(2-Cl)-OMe.HCl)
(S)-(+)-2-Chlorophenylglycine methyl ester, HCl
AS-10889
DTXSID10647829
J-013975
Methyl (2S)-amino(2-chlorophenyl)acetate hydrochloride
213018-92-9
Benzeneacetic acid, alpha-amino-2-chloro-, methyl ester, hydrochloride (1:1), (alphaS)-
methyl (S)-2-amino-2-(2-chlorophenyl)acetate hydrochloride
CS-0210581
Benzeneacetic acid, alpha-amino-2-chloro-, methyl ester, hydrochloride, (alphaS)-
MFCD07368257
(+)-(S)-Methyl alpha-amino-alpha-(2-chlorophenyl)acetate hydrochloride
methyl (2S)-2-amino-2-(2-chlorophenyl)acetate;hydrochloride
7TAX9F47Z5
Methyl (2S)-2-amino-2-(2-chlorophenyl)acetate hydrochloride
Benzeneaceticacid, a-amino-2-chloro-, methyl ester,hydrochloride (1:1), (aS)-
L-(+)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL

MDL Number

MFCD07368257

Customs Code

2922499990

FAQ

What are the physical and chemical properties of (S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride (CAS: 213018-92-9)?

(S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride is a white crystalline powder with a molecular weight of 265.65 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound shows moderate reactivity under acidic conditions. It is stable under normal conditions but should be stored away from strong bases and reducing agents.

How is (S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride (CAS: 213018-92-9) typically synthesized?

(S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride can be synthesized via the esterification of 2-chlorophenylglycine with methanol, followed by the addition of hydrochloric acid to form the hydrochloride salt. The reaction typically yields a high selectivity and good yield, with the use of a catalyst like a Lewis acid to enhance the reaction rate.

What industries use (S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride (CAS: 213018-92-9)?

(S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride is primarily used in the pharmaceutical industry as an intermediate for the synthesis of chiral compounds. It also finds applications in the polymer industry for the production of functional polymers, and in the development of sensors and semiconductors due to its chiral nature.

What precautions should be taken when handling (S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride (CAS: 213018-92-9)?

When handling (S)-(+)-2-Chlorophenylglycine Methyl Ester Hydrochloride, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and heat sources. Use a fume hood during handling to minimize exposure to vapors. In case of a spill, sweep up the material carefully and dispose of it according to hazardous waste regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information.