2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine

Basic Information

View in Editor

CAS Number

210539-05-2

Molecular Formula

C8H9ClN2

Molecular Weight

168.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1CNCC2=C1N=C(C=C2)Cl

InChI

InChI=1S/C8H9ClN2/c9-8-2-1-6-5-10-4-3-7(6)11-8/h1-2,10H,3-5H2

InChIKey

CQDMQOQCJRLUQN-UHFFFAOYSA-N

LogP

1.3807

Topological Polar Surface Area

24.92 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

140

Synonyms & References

English

AM20050939
2-chloro-5,6,7,8-tetrahydro-[1,6]naphthyridine
AKOS006304798
CS-0099551
AS-46987
1,6-Naphthyridine, 2-chloro-5,6,7,8-tetrahydro-
F11138
SCHEMBL868598
A815100
FT-0648481
CQDMQOQCJRLUQN-UHFFFAOYSA-N
AB56356
EN300-120946
METHYLMETHANESULFONYLACETATE
210539-05-2
SY020888
2-Chloro-5,6,7,8-tetrahydro[1,6]naphthyridine, AldrichCPR
MFCD10566728
DTXSID80593905
2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine
2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine
1,6-Naphthyridine,2-chloro-5,6,7,8-tetrahydro-
2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
1,6-Naphthyridine,2-chloro-5,6,7,8-tetrahydro
TRA0054231
RP09346
AB0023363
W4400
5,6,7,8-Tetrahydro-2-chloro-1

MDL Number

MFCD10001474

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS: 210539-05-2)?

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is a solid with a crystalline form. Its molecular weight is approximately 215.57 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It has a low reactivity towards bases and acids.

How is 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS: 210539-05-2) typically synthesized?

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is typically synthesized via a multistep process involving the nucleophilic substitution of naphthyridine with chlorine. Common methods include the use of thionyl chloride and a base such as pyridine. The yield is generally around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity.

What industries use 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS: 210539-05-2)?

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is used in the pharmaceutical industry for the synthesis of certain bioactive compounds. It is also utilized in the development of sensors and in the production of semiconductors due to its electronic properties. Additionally, it has potential applications in the polymer industry for the development of new materials.

What precautions should be taken when handling 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS: 210539-05-2)?

When handling 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a fume hood or a well-ventilated area to minimize exposure. In case of a spill, it should be handled with care, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines.