2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine(CAS: 210539-05-2)

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is a solid with a crystalline form. Its molecular weight is approximately 215.57 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It has a low reactivity towards bases and acids.

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is typically synthesized via a multistep process involving the nucleophilic substitution of naphthyridine with chlorine. Common methods include the use of thionyl chloride and a base such as pyridine. The yield is generally around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity.

2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is used in the pharmaceutical industry for the synthesis of certain bioactive compounds. It is also utilized in the development of sensors and in the production of semiconductors due to its electronic properties. Additionally, it has potential applications in the polymer industry for the development of new materials.

When handling 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a fume hood or a well-ventilated area to minimize exposure. In case of a spill, it should be handled with care, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines.