Amoxicillin EP Impurity C (Amoxicillin Diketopiperazines)

Basic Information

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CAS Number

2088961-37-7

Molecular Formula

C16H19N3O5S

Molecular Weight

365.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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S1C(C2C(NC(C3C=CC(=CC=3)O)C(N2)=O)=O)N[C@@H](C(=O)O)C1(C)C

InChI

1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-14(25-16)10-13(22)17-9(12(21)18-10)7-3-5-8(20)6-4-7/h3-6,9-11,14,19-20H,1-2H3,(H,17,22)(H,18,21)(H,23,24)/t9?,10?,11-,14?/m0/s1

InChIKey

IIZCCQJEPBWGJU-DGVZPSOQSA-N

LogP

-0.05779999999999985

Topological Polar Surface Area

127.76 Å²

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

576

Synonyms & References

English

(4S)-2-(5-(4-hydroxyphenyl)-3,6-dioxopiperazin-2-yl)-5,5-dimethylthiazolidine-4-carboxylic acid
H5BT0J2UDI
Amoxicillin Diketopiperazines
A936519
Q27279664
(4S)-2-[5-(4-hydroxyphenyl)-3,6-dioxopiperazin-2-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
(4S)-2-[5-(4-Hydroxyphenyl)-3,6-dioxopiperazin-2-yl]-5,5-dimethylthiazolidine-4-carboxylic Acid (Amoxicillin Diketopiperazines)
2-[5-(4-Hydroxyphenyl)-3,6-dioxo-2-piperazinyl]-5,5-dimethylthiazolidine-4beta-carboxylic acid
20889
(4S)-2-(5-(4-Hydroxyphenyl)-3,6-dioxopiperazin-2-yl)-5,5-dimethylthiazolidine-4-carboxylic acid

FAQ

What are the physical and chemical properties of Amoxicillin EP Impurity C (CAS: 2088961-37-7)?

Amoxicillin EP Impurity C, also known as Amoxicillin Diketopiperazines, is a crystalline compound with a molecular weight of approximately 268.24 g/mol. It has a low solubility in water and is not very reactive under normal conditions. This impurity is often observed in pharmaceutical formulations of amoxicillin.

How is Amoxicillin EP Impurity C (CAS: 2088961-37-7) typically synthesized?

Amoxicillin EP Impurity C is typically synthesized as a byproduct of the synthesis of amoxicillin. The diketopiperazines are formed through the condensation of amoxicillin with itself or other amino acids, leading to a mixture of impurities, including Amoxicillin EP Impurity C.

What industries use Amoxicillin EP Impurity C (CAS: 2088961-37-7)?

Amoxicillin EP Impurity C is primarily used in the pharmaceutical industry for quality control and impurity profiling of amoxicillin formulations. It is not extensively used in other industries.

What precautions should be taken when handling Amoxicillin EP Impurity C (CAS: 2088961-37-7)?

When handling Amoxicillin EP Impurity C, standard laboratory safety precautions should be followed. Wear appropriate personal protective equipment (PPE), including gloves and goggles, and ensure the use of a fume hood to minimize exposure. Always refer to the Safety Data Sheet (SDS) for specific handling and storage instructions.