({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (1:1) | CAS No. 206184-49-8

({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (1:1)

Basic Information

CAS Number

206184-49-8

Molecular Formula

C9H16N5O5P

Molecular Weight

305.23 g/mol

AD

Basic Physical Properties

Melting Point

293-297°C

Boiling Point

616.1°C at 760 mmHg

Specific Rotation

-18.0° - -22.0° (c=1, 0.1M HCl)

C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(O)O.O

InChI

InChI=1S/C9H14N5O4P.H2O/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14;/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17);1H2/t6-;/m1./s1

InChIKey

PINIEAOMWQJGBW-FYZOBXCZSA-N

LogP

-0.8759000000000003

Topological Polar Surface Area

167.88000000000002 Ų

Hydrogen Bond Donor/Acceptor

6 / 10

Complexity

354

Safety Information

View Safety Information

GHS Hazard Pictograms

H301H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Synonyms & References

English

  • (R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid hydrate
  • 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
  • (r)-[[2-(6-amino-9h-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid monohydrate
  • (R)-9-(2-phosphonylmethoxypropyl)adenine (R-PMPA)
  • (R)-9-(2-phosphonylmethoxy propyl)adenine
  • Tenofovir hydrate
  • R-PMPA
  • GS 1278 hydrate
  • PMPA hydrate
  • TDF hydrate
  • Tenofovir Monohydrate
  • Unii-99yxe507il
  • Tenofovir impurity 7
  • [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate
  • Tenofovir (hydrate)
  • tenofovir.H2O
  • 99YXE507IL
  • Tenofovir [USAN]
  • Tenofovir (USAN)
  • ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid--water (1/1)
  • Viread hydrate
  • C9H16N5O5P
  • BCP11366
  • EBD34584
  • 0568A

MDL Number

MFCD11519982

Customs Code

2933990090

FAQ

What regulatory guidelines apply to ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8)?

({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8) is subject to various regulatory guidelines including GHS classification for hazards, REACH regulations in the EU, and FDA/EPA requirements. It is important to consult specific regulations for storage, handling, and disposal to ensure compliance with local and international laws.

Are there alternatives to ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8) in synthesis?

There are alternative reagents and compounds that can be used in syntheses as substitutes for ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8), such as related phosphonic acids or analogs with similar functional groups. The choice depends on the specific requirements of the synthesis and the desired properties of the final product.

What is the market or research trend for ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8)?

The market for ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8) is growing with increasing research interest in its potential applications in biotechnology and pharmaceuticals. However, the market is niche, and trends suggest a focus on developing more versatile and efficient drug candidates. Research is also exploring its use in diagnostic applications and as a component in advanced medical treatments.

How should waste containing ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8) be handled?

Waste containing ({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonic acid hydrate (CAS: 206184-49-8) should be collected in appropriate containers and stored in a well-ventilated area away from incompatible materials. Incineration or professional waste disposal services should be used for disposal. Proper environmental protection measures, such as containment and neutralization, are essential to prevent environmental contamination. Always consult local regulations for specific disposal procedures.

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