Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (1:1) | CAS No. 204255-09-4
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (1:1)
Basic Information
CAS Number
204255-09-4
Molecular Formula
C16H29ClN2O4
Molecular Weight
348.87 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, monohydrochloride, (3R,4R,5S)-
- 1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester,monohydrochloride, (3R,4R,5S)-
- ethyl (3R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate,hydrochloride
- OSELTAMIVIR HCL
- OSELTAMIVIR MONO HYDROCHLORIDE
- Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
- hydrochloride (1:1)
MDL Number
MFCD09033239
FAQ
What are the physical and chemical properties of Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (CAS: 204255-09-4)?
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride is a crystalline solid with a molecular weight of approximately 457.5 g/mol. It has a low solubility in water but is soluble in organic solvents like DMSO and acetonitrile. The compound is reactive, particularly towards nucleophiles and bases. It exhibits good stability under neutral and slightly acidic conditions.
How is Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (CAS: 204255-09-4) typically synthesized?
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride is synthesized through a multi-step process involving the protection of a primary amine, followed by acetylation, a Wittig reaction, and finally a hydrolysis step. Commonly used catalysts include boron trifluoride and sodium hydride. The yield is typically around 70-80%, with high selectivity to the desired isomer.
What industries use Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (CAS: 204255-09-4)?
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride is primarily used in pharmaceutical and polymer industries. It serves as a precursor for the synthesis of intermediates in drug development and is also utilized in the manufacturing of certain types of polymers, particularly those with enhanced biocompatibility and water solubility.
What precautions should be taken when handling Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (CAS: 204255-09-4)?
When handling Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be immediately cleaned up with appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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