Compound Q&A
How is Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (CAS: 204255-09-4) typically synthesized?
Answer
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride is synthesized through a multi-step process involving the protection of a primary amine, followed by acetylation, a Wittig reaction, and finally a hydrolysis step. Commonly used catalysts include boron trifluoride and sodium hydride. The yield is typically around 70-80%, with high selectivity to the desired isomer.
About
CAS No
204255-09-4
English Name
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate hydrochloride (1:1)
Molecular Formula
C16H29ClN2O4
Molecular Weight
348.8710000000001 g/mol
SMILES
Cl.O=C(OCC)/C1=C/[C@@H](OC(CC)CC)[C@H](NC(=O)C)[C@@H](N)C1
InChIKey
OHEGLAHLLCJYPX-ONAKXNSWSA-N
Last Updated: 2026-03-23 00:14
