Lapatinib Impurity 18

Basic Information

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CAS Number

202197-26-0

Molecular Formula

C13H11ClFNO

Molecular Weight

251.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

78.0 to 82.0 deg-C

Boiling Point

387.9°C at 760 mmHg

Density

1.306

Flash Point

188.4 °C

Refractive Index

1.607

SMILES

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C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)N)Cl

InChI

InChI=1S/C13H11ClFNO/c14-12-7-11(16)4-5-13(12)17-8-9-2-1-3-10(15)6-9/h1-7H,8,16H2

InChIKey

AYPFEYDGZDPAPE-UHFFFAOYSA-N

LogP

3.6403000000000016

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

242

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H341 Suspected of causing genetic defects
Germ cell mutagenicity

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 9 Class 9

Synonyms & References

English

DTXSID10427603
4-(3-fluorobenzyloxy)-3-chloro aniline
3-Chloro-4-((3-fluorobenzyl)oxy)aniline
3-chloro-4-(3-fluoro-benzyloxy)aniline
SY008144
A814338
EC 445-590-4
MFCD06809822
SCHEMBL156718
CS-0008658
TS-00798
Z239873302
AKOS008093322
3-chloro-4(m-fluoro-benzyloxy)-aniline
202197-26-0
AYPFEYDGZDPAPE-UHFFFAOYSA-N
3-chloro-4-[(3-fluorophenyl)methoxy]aniline
3-chloro-4-(m-fluoro-benzyloxy)-aniline
Q2X82DMR4T
3-chloro4-(3-fluorobenzyloxy)aniline
3-chloro-4-(3-fluorobenzyloxy)aniline, AldrichCPR
SB18202
BCP10606
C2874
AC-8505
3-Chloro-4-(3-fluorobenzyloxy)phenylamine
AR-527/43363328
3-CHLORO-4-(3-FLUOROBENZYLOXY)ANILINE
Q-101356
3-chloro-4-(3-fluorobenzyloxy)-aniline
3-chloro-4-[(3-fluorobenzyl)oxy]aniline

MDL Number

MFCD06809822

Customs Code

2922299090

FAQ

What is Lapatinib Impurity 18 (CAS: 202197-26-0)?

Lapatinib Impurity 18 is a chemical compound with the CAS number 202197-26-0. It is an impurity associated with the pharmaceutical drug Lapatinib, which is used in cancer treatment. This compound is typically identified during the synthesis or purification of Lapatinib and may have specific structural and physicochemical properties that differ from the parent drug.

What are the main uses of Lapatinib Impurity 18 (CAS: 202197-26-0)?

Lapatinib Impurity 18 is primarily used in pharmaceutical research and quality control for the analysis and identification of impurities in Lapatinib. It may also be relevant in the development of drug purity standards and in the study of metabolic pathways or degradation products related to Lapatinib in clinical and preclinical settings.

Is Lapatinib Impurity 18 (CAS: 202197-26-0) safe?

Lapatinib Impurity 18 is generally considered safe when handled in accordance with standard laboratory safety protocols. However, as with any chemical compound, it should be treated with care, and appropriate protective measures such as gloves, goggles, and ventilation should be used. Safety data and toxicity profiles are often assessed during drug development to ensure compliance with regulatory guidelines.

How should Lapatinib Impurity 18 (CAS: 202197-26-0) be stored?

Lapatinib Impurity 18 should be stored in a cool, dry place away from direct light. It is typically maintained at a temperature between 2°C to 8°C and kept in a sealed, airtight container to prevent moisture absorption. Proper storage conditions are essential to ensure its stability and prevent any chemical degradation or contamination.