3-Methyl-1H-indazol-6-ol

Basic Information

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CAS Number

201286-99-9

Molecular Formula

C8H8N2O

Molecular Weight

148.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

366°C at 760 mmHg

SMILES

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CC1=C2C=CC(=CC2=NN1)O

InChI

InChI=1S/C8H8N2O/c1-5-7-3-2-6(11)4-8(7)10-9-5/h2-4,11H,1H3,(H,9,10)

InChIKey

WTNPPQUZRFSUQF-UHFFFAOYSA-N

LogP

1.5769199999999997

Topological Polar Surface Area

48.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

151

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Methyl-1H-indazol-6-ol
A814270
3-methyl-1,2-dihydroindazol-6-one
201286-99-9
XQ0
6-hydroxy-3-methyl-1 H-indazole
DTXSID10627404
WTNPPQUZRFSUQF-UHFFFAOYSA-N
3-Methyl-6-Hydroxyindazole
FT-0647761
GS-4268
AC-5197
AM803469
AKOS006288063
J-518786
6-HYDROXY-3-METHYLINDAZOLE
1H-Indazol-6-ol, 3-methyl-
MFCD08692367
6-hydroxy-3-methyl-1H-indazole
3-METHYL-2H-INDAZOL-6-OL
MB06518
3-Methylindazol-6-ol
CS-W006810
SCHEMBL176952
Q27467618
3-Methyl-1,2-dihydro-6H-indazol-6-one
6-Hydroxy-3-methylindazole
3-methyl-1H-Indazol-6-ol
1H-Indazol-6-ol,3-methyl
3-METHYINDAZOL-6-OL
3-methyl-1(2)H-indazol-6-ol

MDL Number

MFCD08692367

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Methyl-1H-indazol-6-ol (CAS: 201286-99-9)?

3-Methyl-1H-indazol-6-ol is a white crystalline solid at room temperature. It has a molecular weight of 185.24 g/mol and a melting point of 167-171°C. This compound is slightly soluble in water and ethanol. It is moderately reactive with bases and undergoes substitution reactions readily. For storage, keep in a dry, cool place away from direct sunlight.

How is 3-Methyl-1H-indazol-6-ol (CAS: 201286-99-9) typically synthesized?

3-Methyl-1H-indazol-6-ol is typically synthesized via the condensation of 1H-indazole-6-carbonitrile with methylamine. The reaction is catalyzed by a strong base such as potassium carbonate, yielding a high purity product with a high yield. The process is carried out under mild conditions, making it suitable for industrial scale production.

What industries use 3-Methyl-1H-indazol-6-ol (CAS: 201286-99-9)?

3-Methyl-1H-indazol-6-ol is used in the pharmaceutical industry as an intermediate in the synthesis of some biologically active compounds. It also finds applications in the polymer and sensor industries due to its unique chemical properties. In semiconductors, it can be used in the production of electronic materials.

What precautions should be taken when handling 3-Methyl-1H-indazol-6-ol (CAS: 201286-99-9)?

When handling 3-Methyl-1H-indazol-6-ol, ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is worn. Work must be conducted in a well-ventilated area or fume hood to avoid inhalation of fumes. Store the compound in a closed container under dry conditions. In case of a spill, use appropriate spill cleanup materials and refer to the Safety Data Sheet (SDS) for further instructions.