3-Methyl-1H-indazol-6-ol(CAS: 201286-99-9)

3-Methyl-1H-indazol-6-ol is a white crystalline solid at room temperature. It has a molecular weight of 185.24 g/mol and a melting point of 167-171°C. This compound is slightly soluble in water and ethanol. It is moderately reactive with bases and undergoes substitution reactions readily. For storage, keep in a dry, cool place away from direct sunlight.

3-Methyl-1H-indazol-6-ol is typically synthesized via the condensation of 1H-indazole-6-carbonitrile with methylamine. The reaction is catalyzed by a strong base such as potassium carbonate, yielding a high purity product with a high yield. The process is carried out under mild conditions, making it suitable for industrial scale production.

3-Methyl-1H-indazol-6-ol is used in the pharmaceutical industry as an intermediate in the synthesis of some biologically active compounds. It also finds applications in the polymer and sensor industries due to its unique chemical properties. In semiconductors, it can be used in the production of electronic materials.

When handling 3-Methyl-1H-indazol-6-ol, ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is worn. Work must be conducted in a well-ventilated area or fume hood to avoid inhalation of fumes. Store the compound in a closed container under dry conditions. In case of a spill, use appropriate spill cleanup materials and refer to the Safety Data Sheet (SDS) for further instructions.