2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate

Basic Information

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CAS Number

199175-10-5

Molecular Formula

C10H20N2O2

Molecular Weight

200.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Liquid

Melting Point

No data available

Boiling Point

280.3°C at 760 mmHg

Density

1.044

Flash Point

123.3℃

Refractive Index

1.4780

Specific Rotation

+21° (c=1 in CHCl3)

SMILES

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CC(C)(C)OC(=O)N1CCC(C1)CN

InChI

InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-5-4-8(6-11)7-12/h8H,4-7,11H2,1-3H3/t8-/m0/s1

InChIKey

OGCCBDIYOAFOGK-QMMMGPOBSA-N

LogP

1.2020999999999997

Topological Polar Surface Area

55.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

211

Safety Information

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GHS Hazard Pictograms

H302

H319

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

(s)-tert-butyl-3-(aminomethyl)pyrrolidine-1-carboxylate
GS-3591
(S)-1-Boc-3-(aminomethyl)pyrrolidine
DTXSID50363899
199175-10-5
(s)-1-n-boc-3-(aminomethyl)pyrrolidine
AMY21278
SCHEMBL6197
CS-W008927
1,1-dimethylethyl(3s)-3-(aminomethyl)-1-pyrrolidinecarboxylate
1-dimethylethyl(3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate
Q-102864
tert-butyl (3S)-3-(amino-methyl)pyrrolidine-1-carboxylate
(3S)-3-Aminomethyl-1-Boc-pyrrolidine
(S)-3-(AMINOMETHYL)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE
OGCCBDIYOAFOGK-QMMMGPOBSA-N
MFCD02179397
tert-butyl (3S)-3-(aminomethyl)pyrrolidine-1-carboxylate
(S)-3-(Aminomethyl)-1-N-Boc-pyrrolidine
EN300-88134
1,1-Dimethylethyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate
(s)-3-aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
(S)-3-(aminomethyl)-1-N-tert-butyloxycarbonylpyrrolidine
AKOS005258695
(S)-3-(Aminomethyl)-1-Boc-pyrrolidine, 95%
3(s)-aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
(s)-tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate
A4363
1,1-dimethylethyl(3S)-3-(amino methyl)-1-pyrrolidinecarboxylate
(S)-1-Boc-3-(Aminomethyl)pyrrolidine
(S)-1-BOC-3-AMINOMETHYLPYRROLIDINE

MDL Number

MFCD02179397

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate (CAS: 199175-10-5)?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is a colorless to white solid with a molecular weight of approximately 255.37 g/mol. It has a melting point of 65-67°C and is slightly soluble in water. The compound is chemically reactive, particularly towards nucleophiles and bases, making it useful in organic synthesis and pharmaceutical applications.

How is 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate (CAS: 199175-10-5) typically synthesized?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is synthesized through a multi-step process involving the coupling of a 2-methyl-2-propanol derivative with a pyrrolidine derivative. The reaction typically requires a base catalyst and is performed under mild conditions. The overall process involves protecting group manipulations and selective functional group transformations to achieve the final product.

What industries use 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate (CAS: 199175-10-5)?

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the semiconductor industry for use in certain chemical vapor deposition processes and as a dopant. Additionally, it may be used in the production of certain polymers and sensors.

What precautions should be taken when handling 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate (CAS: 199175-10-5)?

When handling 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate, it is essential to use appropriate personal protective equipment (PPE) such as gloves and eye protection. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for specific handling and storage instructions to ensure safety in the laboratory environment.