2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate(CAS: 199175-10-5)

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is a colorless to white solid with a molecular weight of approximately 255.37 g/mol. It has a melting point of 65-67°C and is slightly soluble in water. The compound is chemically reactive, particularly towards nucleophiles and bases, making it useful in organic synthesis and pharmaceutical applications.

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is synthesized through a multi-step process involving the coupling of a 2-methyl-2-propanol derivative with a pyrrolidine derivative. The reaction typically requires a base catalyst and is performed under mild conditions. The overall process involves protecting group manipulations and selective functional group transformations to achieve the final product.

2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the semiconductor industry for use in certain chemical vapor deposition processes and as a dopant. Additionally, it may be used in the production of certain polymers and sensors.

When handling 2-Methyl-2-propanyl (3S)-3-(aminomethyl)-1-pyrrolidinecarboxylate, it is essential to use appropriate personal protective equipment (PPE) such as gloves and eye protection. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for specific handling and storage instructions to ensure safety in the laboratory environment.