(Benzyloxy)acetyl chloride

Basic Information

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CAS Number

19810-31-2

Molecular Formula

C9H9ClO2

Molecular Weight

184.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

84-87 °C/0.4 mmHg

Water Solubility

Reacts with water.

Refractive Index

n20/D 1.523(lit.)

SMILES

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C1=CC=C(C=C1)COCC(=O)Cl

InChI

InChI=1S/C9H9ClO2/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2

InChIKey

QISAUDWTBBNJIR-UHFFFAOYSA-N

LogP

1.9686000000000001

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

142

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

2-benzyloxy acetyl chloride
A4344
FT-0622858
J-012791
ACETYL CHLORIDE, (PHENYLMETHOXY)-
2-benzoxyacetyl chloride
2-benzyloxyacetyl chloride
AMY15053
BB 0260994
Benzyloxy acetyl chloride
(benzyloxy)acetyl chloride
alpha-(Benzyloxy)acetyl chloride
(benzyloxy)acetylchloride
Acetyl chloride, (benzyloxy)-
CS-W016979
FD7227
2-(benzyloxy)acetylchloride
Benzyloxy-acetyl chloride
2-(benzyloxy)acetyl chloride
EN300-198150
benzyloxy acetylchloride
AKOS005206716
benzyloxyacetic acid chloride
F2191-0263
DS-13549
Benzyloxyacetyl chloride, 95%
Acetyl chloride, 2-(phenylmethoxy)-
QISAUDWTBBNJIR-UHFFFAOYSA-N
2-phenylmethoxyacetyl chloride
Benzyloxyacetylchloride
DTXSID00941641

MDL Number

MFCD00010768

Customs Code

2918990090

FAQ

What are the physical and chemical properties of (Benzyloxy)acetyl chloride (CAS: 19810-31-2)?

(Benzyloxy)acetyl chloride is a colorless liquid at room temperature. It has a molecular weight of approximately 184.2 g/mol and a boiling point of 85-88°C. It is slightly soluble in water but miscible with organic solvents. Reactivity is high, making it prone to hydrolysis and condensation reactions.

How is (Benzyloxy)acetyl chloride (CAS: 19810-31-2) typically synthesized?

(Benzyloxy)acetyl chloride is commonly synthesized by reacting benzyloxyacetic acid with thionyl chloride. The reaction is carried out in anhydrous conditions to improve yield and selectivity. Typically, the use of a suitable catalyst is not necessary, but drying agents can be used to enhance the reaction rate.

What industries use (Benzyloxy)acetyl chloride (CAS: 19810-31-2)?

(Benzyloxy)acetyl chloride is used in the pharmaceutical industry for the synthesis of various drugs, particularly in the modification of drug molecules. It is also utilized in the production of polymers and as a reagent in chemical sensors and semiconductor manufacturing processes.

What precautions should be taken when handling (Benzyloxy)acetyl chloride (CAS: 19810-31-2)?

When handling (Benzyloxy)acetyl chloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and laboratory coats. The compound should be handled in a well-ventilated area or under a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Safety data sheets (SDS) should always be consulted for detailed handling instructions.