(Benzyloxy)acetyl chloride(CAS: 19810-31-2)

(Benzyloxy)acetyl chloride is a colorless liquid at room temperature. It has a molecular weight of approximately 184.2 g/mol and a boiling point of 85-88°C. It is slightly soluble in water but miscible with organic solvents. Reactivity is high, making it prone to hydrolysis and condensation reactions.

(Benzyloxy)acetyl chloride is commonly synthesized by reacting benzyloxyacetic acid with thionyl chloride. The reaction is carried out in anhydrous conditions to improve yield and selectivity. Typically, the use of a suitable catalyst is not necessary, but drying agents can be used to enhance the reaction rate.

(Benzyloxy)acetyl chloride is used in the pharmaceutical industry for the synthesis of various drugs, particularly in the modification of drug molecules. It is also utilized in the production of polymers and as a reagent in chemical sensors and semiconductor manufacturing processes.

When handling (Benzyloxy)acetyl chloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and laboratory coats. The compound should be handled in a well-ventilated area or under a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Safety data sheets (SDS) should always be consulted for detailed handling instructions.