7-Methoxy-2-methylquinoline

Basic Information

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CAS Number

19490-87-0

Molecular Formula

C11H11NO

Molecular Weight

173.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

286℃ at 760 mmHg

SMILES

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CC1=NC2=C(C=C1)C=CC(=C2)OC

InChI

InChI=1S/C11H11NO/c1-8-3-4-9-5-6-10(13-2)7-11(9)12-8/h3-7H,1-2H3

InChIKey

QEVADHKTNBIYSD-UHFFFAOYSA-N

LogP

2.551820000000001

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

172

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

7-Methoxy-2-methylquinoline
2-Methyl-7-methoxyquinoline
4-AMINO-6-METHOXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
7-Methoxy-2-methyl-chinolin
7-methoxy-2-methyl-quinoline
7-methoxyquinaldine
AK101790
Quinoline, 7-methoxy-2-methyl-
7-Methoxylchinaldin
QEVADHKTNBIYSD-UHFFFAOYSA-N
FCH836471
0084AB
AB52428
7-Methoxy-2-methylquinoline, AldrichCPR
SY037169
OR309227
AX8233329
T6426
2-Methyl-7-Methoxyquinoline
7-METHOXY-2-METHYLQUINOLINE
SCHEMBL424930
DTXSID70443662
AKOS006282112
DS-3750
A880173
F14750
MFCD09787870
DB-065861
CS-0152758
19490-87-0

MDL Number

MFCD09787870

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 7-Methoxy-2-methylquinoline (CAS: 19490-87-0)?

7-Methoxy-2-methylquinoline is a crystalline compound with a molecular weight of approximately 191.18 g/mol. It has a high melting point of around 125-127°C and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. It is slightly basic in nature and exhibits good reactivity towards electrophiles, making it useful in synthetic organic chemistry.

How is 7-Methoxy-2-methylquinoline (CAS: 19490-87-0) typically synthesized?

7-Methoxy-2-methylquinoline can be synthesized via the methylation of 2-methylquinoline followed by methoxylation. Commonly, the reaction involves treating 2-methylquinoline with methyl halide in the presence of a base, followed by the methoxylation step using methyl nitrate and an acid catalyst. The method yields a pure product with good selectivity and yield.

What industries use 7-Methoxy-2-methylquinoline (CAS: 19490-87-0)?

7-Methoxy-2-methylquinoline is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various bioactive compounds and pharmaceuticals. Additionally, it finds applications in the production of organic dyes, polymers, and as a sensor material in analytical chemistry.

What precautions should be taken when handling 7-Methoxy-2-methylquinoline (CAS: 19490-87-0)?

Proper handling of 7-Methoxy-2-methylquinoline requires the use of personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it is recommended to handle it in a well-ventilated area with a fume hood, and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.