7-Methoxy-2-methylquinoline(CAS: 19490-87-0)

7-Methoxy-2-methylquinoline is a crystalline compound with a molecular weight of approximately 191.18 g/mol. It has a high melting point of around 125-127°C and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. It is slightly basic in nature and exhibits good reactivity towards electrophiles, making it useful in synthetic organic chemistry.

7-Methoxy-2-methylquinoline can be synthesized via the methylation of 2-methylquinoline followed by methoxylation. Commonly, the reaction involves treating 2-methylquinoline with methyl halide in the presence of a base, followed by the methoxylation step using methyl nitrate and an acid catalyst. The method yields a pure product with good selectivity and yield.

7-Methoxy-2-methylquinoline is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various bioactive compounds and pharmaceuticals. Additionally, it finds applications in the production of organic dyes, polymers, and as a sensor material in analytical chemistry.

Proper handling of 7-Methoxy-2-methylquinoline requires the use of personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it is recommended to handle it in a well-ventilated area with a fume hood, and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.