L-gamma-Glutamylglycine(CAS: 1948-29-4)

L-gamma-Glutamylglycine (CAS: 1948-29-4) is a crystalline compound with a molecular weight of approximately 152.17 g/mol. It has a solubility of about 40 mg/mL in water. This compound is relatively stable but can undergo hydrolysis under acidic or alkaline conditions. It is used in pharmaceutical applications and research due to its specific reactivity.

L-gamma-Glutamylglycine (CAS: 1948-29-4) is typically synthesized through peptide coupling reactions, often using solid-phase synthesis techniques. The process involves coupling 2-aminoglycine with gamma-glutamyl chloride in the presence of a suitable coupling agent like 1-hydroxybenzotriazole (HOBt) and a catalytic amount of a coupling reagent like N,N'-dicyclohexylcarbodiimide (DCC). The yield is generally high, and the product is purified by techniques such as HPLC.

L-gamma-Glutamylglycine (CAS: 1948-29-4) is primarily used in the pharmaceutical industry for the development of specific drugs. It also finds applications in the sensor industry due to its unique chemical properties, which make it suitable for biosensor development. Additionally, it is utilized in research and development for various biological and biochemical studies.

When handling L-gamma-Glutamylglycine (CAS: 1948-29-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, a lab coat, and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of dust or vapors. Spills should be cleaned up immediately using appropriate absorbents and following the safety data sheet (SDS) guidelines. Always refer to the SDS for specific handling and emergency procedures.