Compound Q&A

How is L-gamma-Glutamylglycine (CAS: 1948-29-4) typically synthesized?

Answer

L-gamma-Glutamylglycine
L-gamma-Glutamylglycine (CAS: 1948-29-4) is typically synthesized through peptide coupling reactions, often using solid-phase synthesis techniques. The process involves coupling 2-aminoglycine with gamma-glutamyl chloride in the presence of a suitable coupling agent like 1-hydroxybenzotriazole (HOBt) and a catalytic amount of a coupling reagent like N,N'-dicyclohexylcarbodiimide (DCC). The yield is generally high, and the product is purified by techniques such as HPLC.

About

CAS No 1948-29-4
English Name L-gamma-Glutamylglycine
Molecular Formula C7H12N2O5
Molecular Weight 204.182 g/mol
SMILES C(CC(=O)NCC(=O)O)C(C(=O)O)N
InChIKey ACIJGUBIMXQCMF-BYPYZUCNSA-N
Last Updated: 2026-03-04 21:36

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