5-Fluoro-2,3-dihydro-4H-chromen-4-one

Basic Information

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CAS Number

188826-32-6

Molecular Formula

C9H7FO2

Molecular Weight

166.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

No data avaiable

Melting Point

No data available

Boiling Point

279.991 ℃ at 760 mmHg

Density

1.298

Flash Point

119.357 °C

Refractive Index

1.54

Vapor Pressure

0.0±0.6 mmHg at 25°C

SMILES

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C1COC2=C(C1=O)C(=CC=C2)F

InChI

InChI=1S/C9H7FO2/c10-6-2-1-3-8-9(6)7(11)4-5-12-8/h1-3H,4-5H2

InChIKey

AVJVYZBPSAQLLA-UHFFFAOYSA-N

LogP

1.7909000000000002

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

193

Safety Information

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Hazard Statement

Synonyms & References

English

5-Fluoro-2,3-dihydro-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5-fluoro-2,3-dihydro-
5-fluoro-3,4-dihydro-2H-1-benzopyran-4-one
188826-32-6
SCHEMBL769070
5-fluorochroman-4-one;5-Fluoro-4-chromanone
AKOS006331876
5-Fluoro-4-Chromanone
AS-31261
5-Fluorochroman-4-one
DTXSID60670460
AM20030234
5-fluoro-2,3-dihydrochromen-4-one
5-fluoro-chroman-4-one
CS-0146608
A813274
AVJVYZBPSAQLLA-UHFFFAOYSA-N
SY022041
FT-0653058
MFCD09743992
4H-1-Benzopyran-4-one,5-fluoro-2,3-dihydro-

MDL Number

MFCD09743992

FAQ

What is 5-Fluoro-2,3-dihydro-4H-chromen-4-one (CAS: 188826-32-6)?

5-Fluoro-2,3-dihydro-4H-chromen-4-one, also known as 5-FU chromenone, is a chromone derivative with a fluoro substituent. It is a white crystalline solid with a molecular formula of C9H7FO2 and a molecular weight of 168.16. This compound exhibits properties such as low solubility in water but good solubility in organic solvents like ethanol and acetone.

What are the main uses of 5-Fluoro-2,3-dihydro-4H-chromen-4-one (CAS: 188826-32-6)?

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) is primarily used as an intermediate in the synthesis of drugs and other chemical compounds. Notably, it is a key intermediate in the production of 5-fluorouracil, a widely used anticancer drug. Additionally, it is used in research and development for various chemical and pharmaceutical applications.

Is 5-Fluoro-2,3-dihydro-4H-chromen-4-one (CAS: 188826-32-6) safe?

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) is generally safe when handled with appropriate precautions. It is important to follow safety guidelines, such as wearing gloves and protective eyewear, to prevent skin and eye contact. Exposure to high temperatures or prolonged periods of light exposure should be avoided to prevent degradation and potential hazards.

How should 5-Fluoro-2,3-dihydro-4H-chromen-4-one (CAS: 188826-32-6) be stored?

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability. It is recommended to store it in amber bottles or other light-protective containers to prevent photodegradation. The optimal storage temperature is between 15-25°C, and the relative humidity should be kept below 60%.