5-Fluoro-2,3-dihydro-4H-chromen-4-one(CAS: 188826-32-6)

5-Fluoro-2,3-dihydro-4H-chromen-4-one, also known as 5-FU chromenone, is a chromone derivative with a fluoro substituent. It is a white crystalline solid with a molecular formula of C9H7FO2 and a molecular weight of 168.16. This compound exhibits properties such as low solubility in water but good solubility in organic solvents like ethanol and acetone.

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) is primarily used as an intermediate in the synthesis of drugs and other chemical compounds. Notably, it is a key intermediate in the production of 5-fluorouracil, a widely used anticancer drug. Additionally, it is used in research and development for various chemical and pharmaceutical applications.

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) is generally safe when handled with appropriate precautions. It is important to follow safety guidelines, such as wearing gloves and protective eyewear, to prevent skin and eye contact. Exposure to high temperatures or prolonged periods of light exposure should be avoided to prevent degradation and potential hazards.

5-Fluoro-2,3-dihydro-4H-chromen-4-one (5-FU chromenone) should be stored in a cool, dry place away from direct sunlight and heat sources to maintain its stability. It is recommended to store it in amber bottles or other light-protective containers to prevent photodegradation. The optimal storage temperature is between 15-25°C, and the relative humidity should be kept below 60%.